Clinical observation of acupuncture and moxibustion for functional dyspepsia due to Yang deficiency of the spleen and stomach  

针灸治疗脾胃阳虚型功能性消化不良临床观察

作　　者：LIU Yan ZHANG Shaozhan DING Yashuang OUYANG Ling LIU Qiong ZHANG Fuqing 刘燕;张少战;丁雅霜;欧阳玲;刘琼;张馥晴(Chenggong Hospital Affiliated to Xiamen University,Xiamen 361003,China;Hunan University of Chinese Medicine,Changsha 410208,China;不详)

机构地区：[1]Chenggong Hospital Affiliated to Xiamen University,Xiamen 361003,China [2]Hunan University of Chinese Medicine,Changsha 410208,China [3]不详

出　　处：《Journal of Acupuncture and Tuina Science》2022年第6期470-475,共6页针灸推拿医学（英文版）

基　　金：This work was supported by the Project of Hunan Provincial Natural Science Foundation of China(湖南省自然科学基金项目,No.2022JJ40301);Fund Project of Hunan Province Education Office(湖南省教育厅科学研究项目,No.21B0369);Scientific Fund Project of Hunan University of Chinese Medicine(湖南中医药大学科研基金项目,No.2021XJJJ013).

摘　　要：Objective To observe the clinical efficacy of acupuncture and moxibustion for functional dyspepsia(FD)due to Yang deficiency of the spleen and stomach.Methods A total of 90 patients meeting the inclusion criteria of FD due to Yang deficiency of the spleen and stomach were randomized into an acupuncture-moxibustion group,an electroacupuncture(EA)group,and a mosapride group by the random number table method,with 30 cases in each group.The mosapride group was treated with mosapride citrate dispersible tablets.The EA group was treated with EA treatment.The acupuncture-moxibustion group was treated with additional moxibustion therapy based on the treatment in the EA group.All three groups took 10 d as one treatment course and 2 courses in total,with a 2-day interval between two courses.The traditional Chinese medicine(TCM)symptoms score,functional digestive disorder quality of life questionnaire(FDDQL)score,oral-colon transit time(OCTT),and serum glucagon-like peptide-1(GLP-1)level was compared before and after treatment among the three groups.And the clinical efficacy was evaluated.Results The total effective rate in the acupuncture-moxibustion group was 96.7%,which was higher than 86.7%in the EA group and 73.3%in the mosapride group,and the total effective rate in the EA group was higher than that in the mosapride group;the inter-group differences were all statistically significant(P<0.05).After treatment,the TCM symptom score in the three groups was lower than that before treatment(P<0.05),and the FDDQL score was higher than that before treatment(P<0.05).The change after treatment in the TCM symptom score in the acupuncture-moxibustion group and the EA group was more significant than that in the mosapride group,and the change in the acupuncture-moxibustion group was more significant than that in the EA group;the inter-group differences were statistically significant(P<0.05).The change after treatment in the FDDQL score in the acupuncture-moxibustion group and the EA group was greater than that in the mosapride grou目的:观察针灸治疗脾胃阳虚型功能性消化不良(FD)的临床疗效.方法:将90例符合脾胃阳虚型FD纳入标准的患者按随机数字表法分为针灸组、电针组和莫沙比利组,每组30例.莫沙比利组予枸橼酸莫沙比利分散片治疗,电针组予电针治疗,针灸组在电针组的基础上加灸法治疗.三组均以10 d为1个疗程,治疗2个疗程,疗程间休息2 d.比较三组患者治疗前后中医症状评分、功能性消化不良生活质量问卷(FDDQL)评分、口-结肠转运时间(OCTT)及血清胰高血糖素样肽-1(GLP-1)水平,并评价临床疗效.结果:针灸组的总有效率为96.7%,高于电针组的86.7%和莫沙比利组的73.3%,且电针组总有效率高于莫沙比利组;组间差异均有统计学意义(P<0.05).治疗后三组患者中医症状评分低于本组治疗前(P<0.05),FDDQL评分高于本组治疗前(P<0.05).针灸组和电针组治疗后中医症状评分变化较莫沙比利组显著,针灸组变化较电针组显著;组间差异均有统计学意义(P<0.05).针灸组和电针组FDDQL评分治疗后变化大于莫沙比利组,针灸组变化大于电针组;组间差异均有统计学意义(P<0.05).治疗后三组患者OCTT低于本组治疗前(P<0.05),血清GLP-1水平高于本组治疗前(P<0.05);针灸组和电针组治疗后OCTT变化较莫沙比利组显著,针灸组变化较电针组显著;组间差异均有统计学意义(P<0.05).针灸组和电针组治疗后血清GLP-1变化大于莫沙比利组,针灸组变化大于电针组;组间差异均有统计学意义(P<0.05).结论:针灸可改善FD患者的临床症状,提高其生活质量,效果优于电针或莫沙比利单独治疗;缩短胃肠运动时间,提高胃肠激素水平可能是其作用机理.

关 键 词：Acupuncture-moxibustion Therapy Acupuncture Therapy ELECTROACUPUNCTURE Thermal Box Moxibustion DYSPEPSIA Quality of Life Yang Deficiency of the Spleen and Stomach Pattern 

分 类 号：R246.1[医药卫生—针灸推拿学]