广东紫珠标准汤剂制备及质量评价  

Preparation and Quality Evaluation of Standard Decoction of Callicarpa Kwangtungensis

作　　者：向燕芬 邓桂珠 甘国兴 卢泳 龙国斌 朱卫星 XIANG Yanfen;DENG Guizhu;GAN Guoxing;LU Yong;LONG Guobin;ZHU Weixing(Qingyuan Hospital of Traditional Chinese Medicine,Qingyuan 511500,China;Engineering Technology Research Center of Fresh Medicine and National Medicine of Guangdong Province,Qingyuan 511500,China)

机构地区：[1]广东省清远市中医院,广东清远511500 [2]广东省鲜药民族医药工程技术研究中心,广东清远511500

出　　处：《中国民族民间医药》2023年第2期24-28,共5页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：广东省中医药局科研项目(No.20202267)。

摘　　要：目的:制备广东紫珠标准汤剂并评价其质量。方法:收集10批广东紫珠药材制备标准汤剂,测定标准汤剂的pH和出膏率,建立标准汤剂的指纹图谱并采用化学计量学方法进行评价。结果:10批广东紫珠标准汤剂的pH为4.4~5.3,出膏率为11.9%~26.1%,指纹图谱有10个共有峰,且10批广东紫珠标准汤剂指纹图谱与对照指纹图谱的相似度均大于0.90。结论:制备的广东紫珠标准汤剂具有一定的代表性,建立的指纹图谱方法可行。Objective To prepare standard decoction of Callicarpa kwangtungensis and evaluate its quality.Method 10 batches of Callicarpa kwangtungensis were collected and prepared for standard decoctions.The pH and extraction rate were determined.The standard decoction fingerprint was established with HPLC and evaluated with chemo-metrics method.Result The pH in 10 batches of Callicarpa kwangtungensis standard decoction were from 4.4 to 5.3,the extraction rates were from 11.9%to 26.1%.10 peaks were identified in the HPLC fingerprint,and the similarity was higher than 0.90 between the fingerprints of 10 batches of standard decoction and the control finger-print.Conclusion The Callicarpa kwangtungensis standard decoction was represent-ative,and the fingerprint method was feasible.

关 键 词：广东紫珠 标准汤剂 指纹图谱 

分 类 号：R284.1[医药卫生—中药学]