Open avenues for carotenoid biofortification of plant tissues  

作　　者：Luca Morelli Manuel Rodriguez-Concepcion 

机构地区：[1]Institute for Plant Molecular and Cell Biology(IBMCP),CSIC-Universitat Polite`cnica de Vale`ncia,46022 Valencia,Spain [2]Department of Biology&CESAM&ECOMARE,Universidade de Aveiro,3810-193 Aveiro,Portugal

出　　处：《Plant Communications》2023年第1期228-237,共10页植物通讯（英文）

基　　金：supported by grants from the Spanish MCIN/AEI/10.13039/501100011033;European NextGeneration EU/PRTR and PRIMA programs to M.R.-C.(PID2020-115810GB-I00 and UToPIQ-PCI2021-121941);supported by CSIC(202040E299);Generalitat Valenciana(PROMETEU/2021/056);funded by a PhD fellowship from“la Caixa”Foundation(INPhINIT program LCF/BQ/IN18/11660004);an EMBO short-term fellowship(ASTF 8907)for a short stay at the University of Neuchatel(Switzerland).

摘　　要：Plant carotenoids are plastidial isoprenoids that function as photoprotectants,pigments,and precursors of apocarotenoids such as the hormones abscisic acid and strigolactones.Humans do not produce carotenoids but need to obtain them from their diet as precursors of retinoids,including vitamin A.Carotenoids also provide numerous other health benefits.Multiple attempts to improve the carotenoid profile of different crops have been carried out by manipulating carotenoid biosynthesis,degradation,and/or storage.Here,we will focus on open questions and emerging subjects related to the use of biotechnology for carotenoid biofortification.After impressive achievements,new efforts should be directed to extend the use of genome-editing technologies to overcome regulatory constraints and improve consumer acceptance of the carotenoid-enriched products.Another challenge is to prevent off-target effects like those resulting from altered hormone levels and metabolic homeostasis.Research on biofortification of green tissues should also look for new ways to deal with the negative impact that altered carotenoid contents may have on photosynthesis.Once a carotenoid-enriched product has been obtained,additional effort should be devoted to confirming that carotenoid intake from the engineered food is also improved.Thiswork involves ensuring post-harvest stability and assessing bioaccessibility of the biofortified product to confirm that release of carotenoids from the food matrix has not been negatively affected.Successfully addressing these challenges will ensure new milestones in carotenoid biotechnology and biofortification.

关 键 词：BIOFORTIFICATION BIOTECHNOLOGY carotenoids plastidial isoprenoids vitamin A 

分 类 号：Q945[生物学—植物学]