儿童不明原因急性重症肝炎的监测和应对  

Surveillance and response to severe acute hepatitis in children with unknown cause

作　　者：李金松[1] 段招军[1] Li Jinsong;Duan Zhaojun(National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)

机构地区：[1]中国疾病预防控制中心病毒病预防控制所,北京102206

出　　处：《中华实验和临床病毒学杂志》2022年第6期719-724,共6页Chinese Journal of Experimental and Clinical Virology

基　　金：国家重点研发计划(2021YFC2301000)。

摘　　要：自2022年4月份以来,多个国家向世界卫生组织(WHO)报告了儿童不明原因急性重症肝炎病例(已排除由肝炎病毒A-E和其它导致急性肝炎的常见病因)较以往大幅增加。这些病例高度散发,发病人群为16岁以下儿童及青少年,病情进展快、症状重。早期病例约10%预后不佳。WHO认为此次不明原因急性重症肝炎事件已成为全球关注的暴发事件。欧盟疾控中心(ECDC)评估其为"令人担忧的公共卫生事件"。本文就此次全球儿童不明原因急性重症肝炎事件的进展、监测和应对等进行综述,供相关领域学者及公共卫生机构参考。Since April 2022,many countries have reported to the World Health Organization(WHO)a significant increase in number of cases with severe acute hepatitis in children with unknown cause(excluding hepatitis virus A-E and other common causes of acute hepatitis).Those cases are highly sporadic.The disease progresses rapidly with severe symptoms.About 10%of early cases have a poor prognosis.WHO declared this incident an outbreak of severe hepatitis of unknown aetiology,while the European Commission for Disease Control and Prevention(ECDC)rated it as a"worrying public health event".This paper reviews the progress,surveillance and response of this outbreak,for the reference of scholars in relevant fields and public health agencies.

关 键 词：急性肝炎 腺病毒 新型冠状病毒 

分 类 号：R725.7[医药卫生—儿科]