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作 者:Cheng Chen Zhi-Peng Liu Wei-Yue Chen Xiang Wang Yun-Hua Liu Yue Wang Xing-Chao Liu Hai-Ning Fan Jie Bai Yan Jiang Yan-Qi Zhang Hai-Su Dai Zhi-Yu Chen
机构地区:[1]Department of Hepatobiliary Surgery,Southwest Hospital,Third Military Medical University(Army Medical University),Chongqing,China [2]Clinical Research Center of Oncology,Lishui Hospital of Zhejiang University,Zhejiang,China [3]Department of Hepatobiliary Surgery,Sichuan Provincial People's Hospital,Chengdu,China [4]Department of Hepatobiliary Surgery,Affiliated Hospital of Qinghai University,Xining,China [5]Department of Health Statistics,College of Military Preventive Medicine,Third Military Medical University(Army Medical University),Chongqing,China
出 处:《iLIVER》2022年第4期245-251,共7页国际肝胆健康(英文)
摘 要:Background and aim:The textbook outcome(TO)is a comprehensive measure that is superior to individual measures for analysis of surgical quality of care.Anatomical hepatectomy(AH)is beneficial in terms of short-term outcomes in patients undergoing resection.This study was performed to investigate the association between AH and achieving the TO for patients with perihilar cholangiocarcinoma(pCCA)treated with curative-intent resection.Methods:This study involved patients who underwent curative-intent resection for newly diagnosed pCCA from January 2013 to January 2018 at three hospitals in China.All patients were divided into two groups according to the type of hepatectomy:the AH group and non-AH group.The incidence and distribution of achieving the TO were compared between the two groups.Univariable and multivariable logistic regression analyses were used to identify independently predictive factors associated with achieving the TO in patients with pCCA.Results:In total,333 patients were enrolled[AH group,225(67.6%);non-AH group,108(32.4%)].The incidence of achieving the TO in all patients was 24.3%,and the incidence was significantly higher in the AH than non-AH group(30.7%vs.11.1%,respectively).Multivariable analysis revealed that AH,total bilirubin concentration of<34μmol/L,maximum tumor size of<3 cm,no macrovascular invasion,and no lymph node metastasis were independently associated with a higher incidence of achieving the TO.Conclusions:The TO was achieved in approximately one-fourth of patients with pCCA who underwent curative-intent resection.The use of AH was more conducive to achieving the TO in patients with pCCA.
关 键 词:Perihilar cholangiocarcinoma Textbook outcome Anatomical hepatectomy Short-term outcome RESECTION
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