贵州中老年人腰椎QCT骨密度及脊柱脆性骨折的骨密度分析  

Bone mineral density of lumbar spine QCT and spinal fragility fractures in middle-aged and elderly people in Guizhou province

作　　者：李小海[1] 谢光友[1] 梁力嵩 刘江勇[1] 曾宪春[1] 王荣品[1] LI Xiaohai;XIE Guangyou;LIANG Lisong;LIU Jiangyong;ZENG Xianchun;WANG Rongpin(Department of Radiology,Guizhou Provincial People's Hospital,Guiyang 550002,China)

机构地区：[1]贵州省人民医院影像科,贵阳550002

出　　处：《实用医学杂志》2023年第1期60-65,共6页The Journal of Practical Medicine

基　　金：国家自然科学基金项目(编号:81960314);贵州省科技支撑计划(编号:黔科合支撑[2019]2810号)。

摘　　要：目的分析贵州省中老年人腰椎QCT骨密度及脊柱脆性骨折的骨密度。方法收集于贵州省人民医院行QCT骨密度体检的50岁以上中老年2380例,分析QCT骨密度值,并以性别、年龄和脊柱脆性骨折进行分组,分析其与骨密度的相关性。结果腰椎QCT骨密度值示骨量正常、骨量减少、骨质疏松、严重骨质疏松者占比分别为80.00%、16.26%、2.82%、0.92%。骨质疏松者占3.74%,女性、男性分别为8.17%、2.52%,女性明显高于男性,差异有统计学意义(χ^(2)=35.769,P<0.001)。低骨量者占16.26%,女性、男性分别为21.40%、14.84%,差异有统计学意义(χ^(2)=12.721,P<0.001)。60岁以上人群随年龄增加,骨密度降低,骨质疏松症患病率逐渐增加,以女性为著,差异有统计学意义(P<0.05)。50~59岁、60~69岁及70~79岁三个年龄段男性和女性骨量减低患病率随着年龄增加而逐渐增加,以女性为著,差异有统计学意义(P<0.05)。42例(1.76%)脊柱脆性骨折,男31例,女11例,差异无统计学意义(P>0.05);骨质疏松症者骨折发生率为14.61%,明显高于非骨质疏松症者(1.27%),差异有统计学意义(P<0.001)。发生脊柱脆性骨折和未发生的骨密度分别为(99.40±41.78)mg/cm^(3)、(141.98±30.56)mg/cm^(3),差异有统计学意义(P<0.001);不同年龄段中老年人脊柱脆性骨折的骨密度均比同年龄段无脊柱脆性骨折者明显降低,差异有统计学意义(P<0.05)。结论腰椎QCT骨密度能准确反映椎体骨量,为预测和防治中老年骨质疏松及脊柱脆性骨折提供定量依据。Objective To analyze the bone mineral density of lumbar spine QCT and spinal fragility fractures in middle-aged and elderly people in Guizhou province.Methods A total of 2,380 middle-aged and elderly patients over 50 who underwent QCT bone mineral density examination in our hospital were enrolled.The QCT bone mineral density value was analyzed,and the correlation between QCT bone mineral density and spinal fragility fracture was analyzed by sex,age and group.Results The proportion of normal bone mass,osteopenia,osteoporosis and severe osteoporosis was 80.00%,16.26%,2.82%and 0.92%,respectively.The incidence of osteoporosis was 3.74%,8.17%in females and 2.52%in males,respectively,which was significantly higher in females than in males(χ^(2)=35.769,P<0.001).The proportion of low bone mass was 16.26%,21.40%in females,and 14.84%in males,respectively,showing statistical significance(χ^(2)=12.721,P<0.001).With the increase of age,the bone mineral density of the population over 60 decreased,and the prevalence of osteoporosis gradually increased,especially in women,with statistical significance(P<0.05).The prevalence of bone mass loss in men and women aged 50~59 years,60~69 years and 70~79 years increased gradually with the increase of age,especially in women(P<0.05).There were 42 cases(1.76%)of spinal fragility fractures,including 31 males and 11 females,showing no significant difference(P>0.05).The incidence of fracture in patients with osteoporosis(14.61%)was significantly higher than that in patients without osteoporosis(1.27%),and the difference was statistically significant(P<0.001).Bone mineral density with and without spinal fragility fracture were(99.40±41.78)mg/cm^(3) and(141.98±30.56)mg/cm^(3),respectively,and the difference was statistically significant(P<0.001).The bone mineral density of the middle aged and the elderly in different age groups was significantly lower than that of the same age group without spinal fragility fracture(P<0.05).Conclusion QCT bone mineral density of lumbar spine can accurately

关 键 词：贵州省 中老年人 定量CT 骨密度 脊柱脆性骨折 

分 类 号：R445.3[医药卫生—影像医学与核医学]