醒脾养胃中药膏方治疗儿童厌食症的临床研究  

Clinical Study on Xingpi Yangwei Chinese Herbal Ointment(醒脾养胃中药膏方)in Treatment of Children Anorexia

作　　者：梁京 马翠翠[1] 段航星 黄倩 张旭 王洪岗 LIANG Jing;MA Cuicui;DUAN Hangxing;HUANG Qian;ZHANG Xu;WANG Honggang(Shijiazhuang Maternal and Child Health Care Hospital,Shijiazhuang Hebei 050000,China)

机构地区：[1]石家庄市妇幼保健院,河北石家庄050000

出　　处：《中医药导报》2023年第1期72-75,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：河北省中医药管理局科研计划项目(2020285)。

摘　　要：目的:观察醒脾养胃中药膏方联合葡萄糖酸钙锌口服溶液治疗儿童厌食症的效果。方法:76例厌食症患儿随机分为对照组和膏方组,每组38例,膏方组给予自拟中药膏剂联合常规治疗,对照组给予常规治疗,疗程4周。治疗前后分别对两组患儿中医症状积分、临床疗效、血清胃泌素(GAS)、胆囊收缩素(CCK)、血红蛋白(HGB)、钙离子(Ca^(2+))及锌离子(Zn^(2+))变化进行统计,并检测肝肾功能。结果:膏方组临床疗效优于对照组(P<0.05)。治疗结束后,两组患儿血清GAS、HGB较治疗前升高,中医症状积分、血清CCK较治疗前下降,差异均有统计学意义(P<0.05),且治疗组优于对照组(P<0.05)。肝、肾功能检测结果证实两组患儿均未发生不良反应。治疗结束后4周两组患儿复发率比较,差异无统计学意义(P>0.05)。治疗结束后12周膏方组复发率低于对照组(P<0.05)。结论:醒脾养胃中药膏方联合微量元素补充剂可明显改善患儿临床症状,改善胃肠激素水平,提高微量元素和血红蛋白水平,降低复发率。Objective:To observe the effect of Xingpi Yangwei Chinese herbal ointment combined with Calcium zinc gluconate oral solution on children with anorexia.Methods:Totally 76 children with this disease were randomly divided into control group and ointment group,38 cases in each group.The ointment group was given self-made Xingpi Yangwei Chinese herbal ointment combined with conventional treatment.The control group was given routine treatment,and the course of treatment was 4 weeks.Before and after treatment,the Chinese medicine symptom scores,clinical efficacy,serum gastrin(GAS),cholecystokinin(CCK),hemoglobin(HGB),trace elements calcium ion(Ca^(2+))and zinc ion(Zn^(2+))were statistically analyzed in the two groups.Liver and kidney functions were also detected.Results:The ointment group showed better treatment effect than control group(P<0.05).After the treatment,the GAS and HGB increased in two groups,while Chinese medicine symptom scores and CCK decreased,with statistically significant difference(P<0.05).There were no serious adverse reactions in either group of patients.There was no significant difference in the recurrence rate between the two groups at the 4th week after treatment(P>0.05).The ointment group showed lower recurrence rate than control group at 12th weeks after the treatment(P<0.05).Conclusion:Xingpi Yangwei Chinese herbal ointment combined with trace element supplements can significantly improve the clinical symptoms of children,improve the levels of gastrointestinal hormones,increase the levels of trace elements and hemoglobin and reduce the probability of recurrence.

关 键 词：儿童厌食症 中药膏方 微量元素 胃肠激素 临床研究 

分 类 号：R272.6[医药卫生—中医儿科学]