葛根素注射液联合手法复位治疗良性阵发性位置性眩晕临床研究  

Clinical Study on Puerarin Injection Combined with Manual Reduction for Benign Paroxysmal Positional Dizziness

作　　者：刘艳贞 朱帅 李萍 LIU Yanzhen;ZHU Shuai;LI Ping

机构地区：[1]南阳南石医院,河南南阳473000

出　　处：《新中医》2022年第23期69-73,共5页New Chinese Medicine

摘　　要：目的:观察葛根素注射液联合手法复位治疗良性阵发性位置性眩晕的临床疗效。方法:选择106例良性阵发性位置性眩晕患者作为研究对象,按随机数字表法分为对照组与研究组各53例。对照组给予手法复位治疗,研究组给予葛根素注射液联合手法复位治疗。比较2组治疗前后叶酸、维生素B_(12)、25-羟维生素D[25(OH)D]、雌二醇(E_(2))、胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)水平,采用前庭症状指数(VSI)评价2组临床症状,采用Berg平衡量表(BBS)评价2组平衡能力,采用眩晕障碍量表(DHI)评价2组生活质量,并比较2组临床疗效。结果:治疗前,2组E_(2)、叶酸、维生素B_(12)、25(OH)D水平比较,差异无统计学意义(P>0.05);治疗后,2组E_(2)、叶酸、维生素B_(12)、25 (OH) D水平均升高(P<0.05),且研究组高于对照组(P<0.05)。治疗前,2组TC、LDL-C、HDL-C、TG水平比较,差异无统计学意义(P>0.05);治疗后,2组TC、LDL-C、TG水平降低(P<0.05),HDL-C水平升高(P<0.05),且研究组TC、LDL-C、TG水平低于对照组(P<0.05),HDL-C水平高于对照组(P<0.05)。治疗前,2组BBS、VSI、DHI评分比较,差异无统计学意义(P>0.05);治疗后,2组BBS评分升高(P<0.05),VSI、DHI评分降低(P<0.05),且研究组BBS评分高于对照组(P<0.05),VSI、DHI评分低于对照组(P<0.05)。研究组治疗总有效率98.11%,高于对照组84.91%(P<0.05)。结论:与单纯手法复位相比,葛根素注射液联合手法复位治疗良性阵发性位置性眩晕可提升患者E_(2)、叶酸、维生素B_(12)、25 (OH) D水平,调节血脂,缓解患者临床症状,提升患者平衡能力、生活质量,并提高临床疗效。Objective:To observe the clinical effect of the therapy of Puerarin Injection combined with manual reduction for benign paroxysmal positional dizziness.Methods:A total of 106 patients with benign paroxysmal positional dizziness were selected as the research objects and divided into the control group and the study group according to the random number table method,with 53 cases in each group.The control group was treated with manual reduction,and the study group was treated with Puerarin Injection combined with manual reduction.Before and after treatment,the levels of folic acid,vitamin B12,25-hydroxyvitamin D[25(OH)D],estradiol(E_(2)),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and triglyceride(TG) were compared between the two groups.The clinical symptoms in the two groups were evaluated by Vestibular Symptom Index(VSI),the balance ability by Berg balance scale(BBS),and quality of life by Dizziness Handicap Inventory(DHI).The clinical effects were compared between the two groups.Results:Before treatment,there was no significant difference being found in the comparisons of levels of E_(2),folic acid,vitamin B12and 25(OH)D between the two groups(P>0.05);after treatment,the levels of E_(2),folic acid,vitamin B12and 25(OH)D in the two groups were increased when compared with those before treatment(P0.05);after treatment,the levels of TC,LDL-C and TG in the two groups were decreased when compared with those before treatment(P0.05);after treatment,the scores of BBS in the two groups were increased when compared with those before treatment(P<0.05),the scores of VSI and DHI were decreased(P<0.05),the score of BBS in the study group was higher than that in the control group,and the scores of VSI and DHI in the study group were lower(P<0.05).The total effective rate was 98.11% in the study group,higher than that of 84.91% in the control group(P<0.05).Conclusion:Comparing with simple manual reduction,the therapy of Puerarin Injection combined with manual reduc

关 键 词：良性阵发性位置性眩晕 葛根素注射液 手法复位 维生素B_(12) 平衡能力 生活质量 

分 类 号：R764.3[医药卫生—耳鼻咽喉科]