河南省86例儿童新冠肺炎奥密克戎变异株感染患儿的中医临床特征及证候分布规律  

TCM Clinical Characteristics and Syndrome Distribution of 86 Children Infected with Omicron Variant of COVID-19 in Henan Province

作　　者：孙晓旭[1,2] 任献青[1,2] 闫永彬 丁樱[1,2] 张霞[1,2] 段凤阳[1,2] 刘玲玲[1,2] 苏杭[1,2] 苏素静 张勇[1,2] SUN Xiaoxu;REN Xianqing;YAN Yongbin;DING Ying;ZHANG Xia;DUAN Fengyang;LIU Lingling;SU Hang;SU Sujing;ZHANG Yong(The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou Henan China 450000;School of Pediatric Medicine,Henan University of Chinese Medicine,Zhengzhou Henan China 450000)

机构地区：[1]河南中医药大学第一附属医院,河南郑州450000 [2]河南中医药大学儿科医学院,河南郑州450000

出　　处：《中医学报》2023年第2期427-431,共5页Acta Chinese Medicine

基　　金：国家中医药管理局新型冠状病毒感染肺炎中医药应急专项课题项目(2022ZYLCYJ01-2);2022年度河南省中医药科学研究专项课题项目(2022ZYZD03)。

摘　　要：目的:分析河南儿童新冠肺炎奥密克戎变异株患儿的中医临床特征及证候分布规律,为进一步优化河南儿童新冠肺炎奥密克戎变异株中医辨证诊疗方案提供依据。方法:基于国家卫生健康委办公厅、国家中医药管理局办公室发布《新型冠状病毒感染的肺炎诊疗方案》试行第三至八版,结合回顾新冠肺炎临床特征相关文献,咨询医疗救治专家经验,制订“河南儿童新冠肺炎奥密克戎变异株中医临床调查表”。采集86例患儿一般资料、临床症状、舌脉、理化检查、治疗用药等信息,采用双采双检法进行核酸转阴测定;采用描述性分析法、样品聚类法、二次归一统计分析法对临床症状、证候规律、舌脉进行分析,探讨儿童新冠肺炎奥密克戎变异株患儿的中医临床特征及证候分布规律。结果:(1)一般资料:共收治患儿86例,性别比为11.39;平均年龄9岁;中位潜伏时间6(1,11) d;无症状型6例(6.96%),轻型73例(84.9%),普通型7例(8.14%),重型以上0例。(2)实验室检查:核酸转阴中位时间18(5,31) d。(3)临床症状:以发热、咳嗽、有痰、流涕、鼻塞、纳差等呼吸道症状为主。(4)证候分布:风热袭表证66例(76.74%),其中兼夹他证6例、伤阴14例;风寒束表证16例(18.60%),其中兼夹他证5例、伤阴2例;风燥犯表证2例(2.33%);痰热蕴肺证2例(2.33%),其中兼夹他证1例。(5)证候传变:86例患儿证候无传变者75例(87.2%);风热袭表证传变7例;风寒束表证传变4例。结论:河南儿童新冠肺炎奥密克戎变异株核心病机为风热袭肺,中医证型以风热袭表证为主,经扶正祛邪治疗后,大部分患儿未出现证候传变,证候传变患儿则以卫分顺传气分为主,少数出现卫分证直传阳明;经治疗患儿临床症状消失,核酸全部转阴。Objective:To analyze the TCM clinical characteristics and syndrome distribution of children with Omicron variant of COVID-19 in Henan province,and to provide a basis for further optimization of TCM syndrome differentiation diagnosis and treatment plan for Children with Omicron variant of COVID-19 in Henan Province.Methods:Based on the 3-8 editions of the COVID-19 Diagnosis and Treatment Protocol released by the General Office of the NHC and the Office of the National Administration of Traditional Chinese Medicine,combined with reviewing the relevant literature on the clinical characteristics of COVID-19,and consulting the experience of medical treatment experts,the "TCM Clinical Questionnaire for Children with Omicron variant of COVID-19 in Henan province" was formulated.The general information,clinical symptoms,tongue pulse,physical and chemical examination,treatment medication,and other information of 86 cases of children were collected,and the nucleic acid negative conversion was determined by double sampling and double detection method.The descriptive analysis method,sample clustering method,and quadratic normalized statistical analysis method were used to analyze the clinical symptoms,syndrome rules,and tongue pulse,and to explore the TCM clinical characteristics and syndrome distribution of children with Omicron variant of COVID-19.Results:(1)General information:A total of 86 children were admitted,with a sex ratio of 1■1.39.The average age was 9 years old.The median latency time was 6 days(1,11).With 6 asymptomatic cases(6.96%),73 cases mild(84.9%),7 normal cases(8.14%),and 0 severe cases.(2)Laboratory examination:The median time of nucleic acid turning negative was 18 days(5,31).(3)Clinical symptoms:mainly respiratory symptoms such as fever,cough,sputum,runny nose,nasal congestion,and poor appetite.(4)Syndrome distribution:66 cases(76.74%) were Wind-Heat assaulting exterior syndrome,including 6 cases with other syndromes and 14 cases with Yin injury.16 cases(18.60%) were Wind-Cold tightening exterior sy

关 键 词：新型冠状病毒肺炎 奥密克戎变异株 儿童 河南省 中医临床特征 证候 

分 类 号：R254.2[医药卫生—中医内科学]