直接冻黄G的绿色制备工艺研究  

Study on green preparation technology of Chrysophenine G^(*)

作　　者：刘晨义 路朝阳 王柏楠 王延花[2,4] 霍二福 LIU Chen-yi;LU Zhao-yang;WANG Bo-nan;WANG Yan-hua;HUO Er-fu(Pingdingshan Mingyuan Chemical Co.,Ltd.,Pingdingshan 467000,China;Henan Chemical Industry Institute Co.,Ltd.,Zhengzhou 450052,China;Quality Inspection and Analytical Test Research Center,Henan Academy of Sciences,Zhengzhou 450008,China;Fine Chemical Intermediate Engineering Technology Research Center of Henan Province,Zhengzhou 450052,China)

机构地区：[1]平顶山市铭源化工有限公司,河南平顶山467000 [2]河南省化工研究所有限责任公司,河南郑州450052 [3]河南省科学院质量检验与分析测试研究中心,河南郑州450008 [4]河南省精细化工中间体工程技术研究中心,河南郑州450052

出　　处：《化学工程师》2023年第1期14-18,共5页Chemical Engineer

基　　金：河南省科学院重大科研项目聚焦项目(210108004);杰青人才培养项目(200408004)。

摘　　要：以4,4'-二氨基二苯乙烯-2,2'-二磺酸(DSD酸)为起始原料依次与NaNO_(2)、苯酚和氯乙烷反应,分别经重氮化、偶合、醚化反应,经过滤、烘干、粉碎得直接冻黄G。重氮化、偶合、醚化反应均采用乙醇为反应溶剂,反应后乙醇回收、重复利用,避免采用大量水为反应溶剂产生大量的高盐废水,从源头上解决了大量工业高盐废水产生的问题,实现了直接冻黄G的绿色制备工艺。Using 4,4'-diaminostilbene-2,2'-disulfonic acid(DSD acid)as the starting material,it reacts with sodium nitrite,phenol and chloroethane successively.After diazotization,coupling and etherification respectively,it is filtered,dried and crushed to obtain Chrysophenine G.Ethanol is used as the reaction solvent for diazotization,coupling and etherification.After the reaction,the ethanol is recycled and reused to avoid using a large amount of water as the reaction solvent to produce a large amount of high salt wastewater.The problem of producing a large amount of industrial high salt wastewater is solved from the source,and the green preparation method of Chrysophenine G is realized,which provides technical support for the implementation of industrialization.

关 键 词：直接冻黄G 乙醇回收利用 工艺优化 绿色制备工艺 

分 类 号：O626.2[理学—有机化学]