单次屏气左心室人工智能辅助压缩感知T_(2)加权黑血成像序列的临床应用  

Clinical application of single breath-holding left ventricle artificial intelligence assisted compression sensing T_(2)-weighted dark blood imaging sequence

作　　者：严祥虎 罗毅[1] 冉玲平 张诗雨 夏黎明[1] 黄璐[1] Yan Xianghu;Luo Yi;Ran Lingping;Zhang Shiyu;Xia Liming;Huang Lu(Department of Radiology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;United Imaging Healthcare,Shanghai 200000,China)

机构地区：[1]华中科技大学同济医学院附属同济医院放射科,武汉430030 [2]上海联影医疗科技股份有限公司,上海200000

出　　处：《中华放射学杂志》2023年第1期48-53,共6页Chinese Journal of Radiology

基　　金：国家自然科学基金(81873889);湖北省科技计划青年基金(2021CFB060)。

摘　　要：目的探讨基于人工智能辅助压缩感知(ACS)的单次激发心脏T_(2)加权黑血序列(T_(2)W-DB)在临床心脏MR检查的应用价值。方法前瞻性收集2021年8至12月在华中科技大学同济医学院附属同济医院38例因临床需要行心脏MR检查的患者。所有患者均进行左心室连续短轴面常规T_(2)W-DB序列和单次激发ACS T_(2)W-DB序列扫描,记录采集时间,分别对这两组序列的图像质量采用客观定量和主观评分两种评估方法进行分析。图像质量客观定量评价分别计算两组序列图像的中间段室间隔心肌信噪比(SNR)、室间隔与血池的对比噪声比(CNR)和锐利度。图像质量主观评价分别对两组序列图像的总体图像质量、血池抑制效果及右心室游离壁、左心室游离壁、室间隔的可视性进行Likert量表评分。分别采用组内相关系数和Kendall W系数评价测量者间图像质量的客观定量指标和观察者间主观评分的一致性,并采用配对t检验或Wilcoxon检验比较常规T_(2)W-DB和单次激发ACS T_(2)W-DB的图像质量客观定量指标、主观评分以及采集时间。结果单次激发ACS T_(2)W-DB和常规T_(2)W-DB在测量者间图像质量客观定量指标和观察者间主观评分具有较好的一致性(P值均<0.05)。相较于常规T_(2)W-DB[(85.8±14.7)s],单次激发ACS T_(2)W-DB[(16.9±3.0)s]缩短了采集时间,差异具有统计学意义(t=35.42,P˂0.001)。相较于常规T_(2)W-DB的SNR(66.4±29.0)和CNR(61.8±28.6),单次激发ACS T_(2)W-DB具有更高的SNR(110.8±36.8)和CNR(88.2±31.1),差异具有统计学意义(t值分别为-8.13、-5.89,P˂0.001)。相较于常规T_(2)W-DB[(4.6±0.6)分],单次激发ACS T_(2)W-DB[(4.7±0.5)分]具有更好的血池抑制效果,差异具有统计学意义(Z=-2.64,P=0.008)。在总体图像质量及右心室游离壁、左心室游离壁、室间隔的可视性上差异没有统计学意义(P>0.05)。结论与常规T_(2)W-DB序列相比,左心室单次激发ACS-T_(2)W-DB序列可以Objective To explore the feasibility of cardiac T2 weighted dark blood sequence(T2W-DB)based on artificial intelligence assisted compression-sensing(ACS)in clinical cardiac MR examination,compared with the conventional cardiac fast spin-echo T2W-DB sequence.Methods A total of 38 patients referred for cardiac MR examination in Tongji Hospital were enrolled prospectively from August to December 2021.The conventional T2W-DB scan and the single-shot ACS T2W-DB scan were acquired at continuous short-axial slices covering the whole left ventricle in all patients,and the acquisition time of each scan was recorded.The image quality of the two sequences was evaluated by the objective quantitative parameters and the subjective scoring methods,respectively.The signal to noise ratio(SNR),the contrast to noise ratio of the interventricular septum to blood pool(CNR),and the sharpness of the images were calculated.The subjective scoring was to evaluate the overall image quality,the effect of blood pool suppression,the visibility of right ventricular free wall,left ventricular free wall,and interventricular septum with a 5-point Likert scale.The intraclass correlation coefficient and Kendall W were calculated to evaluate the interobserver agreement of the objective quantitative parameters and subjective scoring.The paired t-test or Wilcoxon test was used to compare the difference in acquisition time,objective quantitative parameters and subjective scoring between the conventional T2W-DB and the single-shot ACS T2W-DB.Results The inter-observer agreement between the single-shot ACS T2W-DB and conventional T2W-DB was good in all the objective quantitative parameters and subjective scoring of image quality(P<0.05 for all).Compared with conventional T2W-DB,acquisition time of single-shot ACS T2W-DB was remarkably shortened[(85.8±14.7)s vs.(16.9±3.0)s,t=35.42,P<0.001].Compared with SNR(66.4±29.0)and CNR(61.8±28.6)of conventional T2W-DB,single-shot ACS T2W-DB had significantly higher SNR(110.8±36.8,t=-8.13,P˂0.001)and CNR(88.2±

关 键 词：磁共振成像 人工智能 压缩感知 T_(2)加权黑血 

分 类 号：R445.2[医药卫生—影像医学与核医学]