京津冀自然人群队列研究的经验与展望  

General population cohort study in Beijing-Tianjin-Hebei area:past and future

作　　者：何慧婧[1] 潘利[1] 张玲 袁聚祥 刘功姝[4] 张敏英[5] 胡耀达 涂吉 单广良[1] He Huijing;Pan Li;Zhang Ling;Yuan Juxiang;Liu Gongshu;Zhang Minying;Hu Yaoda;Tu Ji;Shan Guangliang(Department of Epidemiology and Statistics,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,School of Basic Medicine,Peking Union Medical College,Beijing 100005,China;Department of Epidemiology and Health Statistics,School of Public Health,Capital Medical University,Beijing 100069,China;Department of Preventive Medicine,School of Public Health,North China University of Science and Technology,Tangshan 063210,China;Research Program Team,Tianjin Women and Children Health Center,Tianjin 300072,China;Department of Public Health,School of Medicine,Nankai University,Tianjin 300071,China)

机构地区：[1]中国医学科学院基础医学研究所/北京协和医学院基础学院流行病与卫生统计学系,北京100005 [2]首都医科大学公共卫生学院流行病与卫生统计学系,北京100069 [3]华北理工大学公共卫生学院预防医学系,唐山063210 [4]天津市妇女儿童保健中心科研项目组,天津300072 [5]南开大学医学院公共卫生学系,天津300071

出　　处：《中华流行病学杂志》2023年第1期7-13,共7页Chinese Journal of Epidemiology

基　　金：国家重点研发计划“精准医学研究”重点专项(2016YFC0900600,2016YFC0900601);中国医学科学院医学与健康科技创新工程(2019-I2M-2-007,2020-I2M-2-009)。

摘　　要：京津冀自然人群队列研究是一项大规模前瞻性队列研究,2017年在北京市、天津市和河北省开展基线调查,覆盖了从生命早期直至老年的114850名调查对象。截至2021年12月,106031人已完成至少1次随访,总体随访率为92.3%。本队列结合三地环境和健康问题特点,重点围绕儿童青少年生长发育、心血管代谢疾病及其危险因素、老龄化及共病、空气污染的健康效应等主题进行了系统研究。京津冀自然人群队列中全生命期多样化人群的长期随访将为我国健康与疾病研究提供独特和宝贵的科研资源以及丰富的生物样品。本文描述了京津冀自然人群队列的产生背景和战略意义、研究现状和成果、不足和挑战以及未来规划和展望等,以期为国内外学者开展相关研究提供参考。The general population cohort study in Beijing-Tianjin-Hebei area is a large-scale prospective longitudinal study conducted since 2017,which covers over 114850 diverse populations from early life to senior age.Up to December 2021,106031 people had completed at least one follow-up,with an overall follow-up rate of 92.3%.Considering of the characteristics of the environmental and health problems in Beijing-Tianjin-Hebei area,in this cohort study we have focused on health problems of children and adolescents'growth and development,cardiometabolic diseases and their risk factors,aging and comorbidity,health hazards caused by air pollution.The long-term follow up of the general population cohort study in Beijing-Tianjin-Hebei area will contribute to establishing unique and invaluable data and biobank resource for scientific research.This paper aims to comprehensively describe the background,significance,current status and outcomes,limitations and challenges,and future plan and development of general population cohort study in Beijing-Tianjin-Hebei area,thus to provide reference for professionals both at home and abroad to carry out related research.

关 键 词：队列研究 自然人群 

分 类 号：R195[医药卫生—卫生统计学]