早期气管切开联合亚低温冬眠疗法在重型颅脑损伤中的临床应用  

Clinical Application of Early Tracheotomy Combined with Mild Hypothermia Hibernation Therapy in Severe Craniocerebral Injury

作　　者：武云龙[1] WU Yunlong(Lianjiang People's Hospital,Lianjiang 524400,China)

机构地区：[1]廉江市人民医院,广东廉江524400

出　　处：《中外医学研究》2023年第3期25-28,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：湛江市科技计划项目(2020B01185)。

摘　　要：目的:分析早期气管切开联合亚低温冬眠疗法在重型颅脑损伤中的临床效果。方法:选择廉江市人民医院2020年1月—2022年1月收治的60例重型颅脑损伤诊断标准的患者,按照随机数表法分成对照组和治疗组,各30例。对照组给予抗炎、止咳化痰等传统药物治疗,治疗组给予早期气管切开联合亚低温冬眠疗法,治疗后观察两组的临床疗效,评价治疗前后两组的脑功能、日常生活能力、住院时间及并发症发生情况。结果:治疗组的临床总有效率为73.33%,高于对照组的36.67%,差异有统计学意义(P<0.05)。治疗后,治疗组的美国国立卫生研究院卒中量表(NIHSS)评分为(19.83±3.24)分,低于对照组的(24.18±3.17)分,简易精神状态评价量表(MMSE)、日常生活活动能力表(ADL)评分分别为(29.39±2.82)、(85.53±4.12)分,高于对照组的(25.14±2.23)、(60.41±4.25)分(P<0.05)。治疗组的ICU住院时间、总住院时间分别为(10.08±2.11)、(20.48±2.31)d,显著短于对照组的(15.46±1.96)、(25.64±1.73)d,差异有统计学意义(P<0.05)。治疗组的并发症发生率为6.67%,低于对照组的26.67%,差异有统计学意义(P<0.05)。结论:早期气管切开联合亚低温冬眠疗法能显著提高患者的临床疗效,促进脑功能恢复,减少并发症发生、缩短住院时间和提高患者日常生活能力,值得推广和应用。Objective:To analyze the clinical effect of early tracheotomy combined with mild hypothermia hibernation in severe craniocerebral injury.Method:A total of 60 patients with severe craniocerebral injury admitted to Lianjiang People’s Hospital from January 2020 to January 2022 were selected and divided into the control group and the treatment group according to the random number table method,with 30 cases in each group.The control group was treated with traditional drugs such as anti inflammation,cough relieving and phlegm resolving.The treatment group was treated with early tracheotomy combined with mild hypothermia hibernation.After treatment,the clinical effects of the two groups were observed,and the brain function,daily living ability,hospital stay and complications of the two groups were evaluated before and after treatment.Result:The total clinical effective rate in the treatment group was 73.33%,which was higher than 36.67%in the control group,the difference was statistically significant(P<0.05).After treatment,the National Institute of Health stroke scale(NIHSS)score in the treatment group was(19.83±3.24)points,which was lower than(24.18±3.17)points in the control group,while the mini mental status examination(MMSE)and activities of daily living scale(ADL)scores were(29.39±2.82)points and(85.53±4.12)points respectively,which were higher than(25.14±2.23)points and(60.41±4.25)points in the control group(P<0.05).The length of stay in the ICU and the total length of stay in the treatment group were(10.08±2.11)d and(20.48±2.31)d respectively,which were significantly shorter than(15.46±1.96)d and(25.64±1.73)d in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the treatment group was 6.67%,which was lower than 26.67%in the control group,the difference was statistically significant(P<0.05).Conclusion:Early tracheotomy combined with mild hypothermia hibernation therapy can significantly improve the clinical efficacy of patients,promote the recove

关 键 词：重症颅脑损伤 早期气管切开 亚低温 临床疗效 

分 类 号：R651.15[医药卫生—外科学]