细菌间纳米管结构、形成分子机制及功能的研究进展  

Resent advance in the structure,formation molecular mechanism and function of bacterial nanotubes

作　　者：罗红 胡龙华[1] 陈艳慧[1] 钟桥石[1] Luo Hong;Hu Long-hua;Chen Yan-hui;Zhong Qiao-shi(Clinical Laboratory of the Second Affiliated Hospital of Nanchang University,Jiangxi Provincial Laboratory of Medicine,Nanchang 330006)

机构地区：[1]南昌大学第二附属医院检验科,江西省检验医学重点实验室,南昌330006

出　　处：《中国抗生素杂志》2022年第12期1249-1253,共5页Chinese Journal of Antibiotics

基　　金：江西省自然基金面上项目(No.20181BAB205066);江西省青年自然基金项目(No.20171BAB215079);江西省卫生健康委科技计划(No.20195211);江西省自然科学基金(No.20202BABL216039)。

摘　　要：纳米管是细菌间形成的一种细胞膜样的管状结构,可介导细菌间的分子交换。研究表明,自然界中大部分微生物具备形成纳米管的潜力,纳米管作为一种促进细菌间物质传递的新机制,受到国内外的高度关注。但是目前对纳米管形成的分子机制、组成成分及物质传递机制尚不完全清楚。本文通过对纳米管的结构、形成的分子机制及细菌间纳米管介导的物质传递等相关研究进行简要综述,旨在为抗病原菌感染提供新的策略。Nanotubes,membrane-derived apparatus,connect adjacent cells and serve as a bridge for intercellular molecular trade.Researches show that nanotube biogenesis is likely to occur in a large array of microbial species.As a mechanism for molecular trafficking,nanotubes have drawn widespread attention both in domestic and abroad.However,the components,formation and molecular trafficking mechanism of bacterial nanotubes are not completely clear yet.In this brief review,bacterial nanotubes are summarized from its structure,molecular mechanism of formation and function,in order to provide a new strategy for fighting against pathogens.

关 键 词：细菌 纳米管 物质交换 

分 类 号：R978.1[医药卫生—药品]