金华地区幽门螺旋杆菌感染情况及抗体分型分析  

Analysis of Helicobacter pylori infection and antibody typing in Jinhua area

作　　者：方莉萍[1] 冯胜春[1] 朱亦璇 吴俊琪[1] FANG Li-ping;FENG Sheng-chun;ZHU Yi-xuan;WU Jun-qi(Laboratory Department,Jinhua Central Hospital,Zhejiang 321000,China)

机构地区：[1]金华市中心医院检验科,浙江321000

出　　处：《中国卫生检验杂志》2022年第23期2870-2872,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的 探讨金华地区幽门螺旋杆菌的感染情况和抗体分型分布特征。方法 采用胶体金法检测2019年1月—2021年12月因消化道疾病就诊于金华市中心医院2 060例患者幽门螺旋杆菌感染抗体分型。结果 幽门螺旋杆菌总阳性率为51.70%(1 065/2 060),其中幽门螺旋杆菌Ⅰ型和Ⅱ型总阳性率分别为32.86%和18.83%,在阳性患者中占比分别为63.57%(677/1 065)和36.43%(388/1 065);男性和女性幽门螺旋杆菌Ⅰ型及Ⅱ型阳性率比较差异无统计学意义(P>0.05);总感染率较高年龄段为51岁~70岁,临床上总阳性率>50%的相关疾病依次是消化道出血、肠溃疡、肠息肉、肠炎、消化道肿瘤和胃功能紊乱。结论 金华地区幽门螺旋杆菌感染人群年龄段主要集中在51岁~70岁,以Ⅰ型感染为主,近3年总阳性率呈下降趋势,但是近年感染幽门螺旋杆菌Ⅰ型占比有增加风险,感染情况与性别无关,临床上主要与消化道等疾病相关,需要引起相关科室关注。Objective This study aims to explore the infection situation and antibody typing distribution characteristics of Helicobacter pylori in Jinhua area. Methods The colloidal gold method was used to detect the classification of 2 060 patients in Jinhua Central Hospital from January 2019 to December 2021 due to gastrointestinal disease. Results The total positive rate of Helicobacter pylori was 51.70%(1 065/2 060). The total positive rates of Helicobacter pylori type Ⅰ and type Ⅱ were 32.86% and 18.83% respectively, accounting for 63.57%(677/1 065) and 36.43%(388/1 065), respectively. There was no statistical significance on the difference in the positive rates of Helicobacter pylori type Ⅰ and type Ⅱ between males and females(P>0.05);the age group with the highest total infection rate is 51 to 70 years old, and the clinically related diseases with a total positive rate greater than 50% were gastrointestinal bleeding, intestinal ulcers, intestinal polyps, enteritis, gastrointestinal tumors and gastric disorders. Conclusion The age of Helicobacter pylori infection in Jinhua area is mainly concentrated in the stage of 51 to 70 years old, and Helicobacter pylori type Ⅰ infection is the main type. The total positive rate has shown a downward trend in the past three years. In recent years, the risk of Helicobacter pylori type Ⅰ infection has increased, and the infection status has nothing to do with gender. Clinically, it is mainly related to diseases such as the digestive tract, and needs to be concerned by relevant departments.

关 键 词：幽门螺旋杆菌 抗体分型 金华地区 

分 类 号：R446.5[医药卫生—诊断学]