22例儿童急性痘疮样苔藓样糠疹临床与病理分析  

Clinical and pathological analysis of 22 children with pityriasis lichenoides et varioliformis acuta

作　　者：钱莹莹 钱华[1] 李巍[1] 鲁慧[1] 胡翠[1] 张婷[1] 李纪兵 吴亚芬[1] QIAN Yingying;QIAN Hua;LI Wei;LU Hui;HU Cui;ZHANG Ting;LI Jibing;WU Yafen(Children's Hospital of Soochow University,Suzou 215000,China)

机构地区：[1]苏州大学附属儿童医院,江苏苏州215000

出　　处：《中国麻风皮肤病杂志》2023年第3期163-166,共4页China Journal of Leprosy and Skin Diseases

基　　金：苏州市医疗卫生应用基础研究项目(编号:sys2018076)。

摘　　要：对22例儿童急性痘疮样苔藓样糠疹(pityriasis lichenoides et varioliformis acuta, PLEVA)患儿的临床资料进行回顾分析。结果示22例患儿中,男女比例2.67∶1,平均年龄(8.77±2.84)岁。皮损分布:弥漫型18例(81.82%),中心型3例(13.64%),外周型1例(4.55%)。16例(72.73%)患儿发病前有上呼吸道或其他感染史。组织病理的共同特征是:基底细胞不同程度的液化变性,真皮浅层或深层血管周围炎。所有患儿均采取联合治疗,包括:系统使用免疫球蛋白、糖皮质激素、复方甘草酸苷、红霉素等并联合外用药物治疗,20例(90.91%)患儿治愈。The data of 22 children with pityriasis lichenoides et varioliformis acuta(PLEVA) were retrospectively analyzed. The result showed the male to female ratio was 2.67∶1, and the average age was(8.77±2.84) years old. The lesions of diffuse type were in 18 cases(81.82%), central type were in 3 cases(13.64%), peripheral type were in 1 cases(4.55%). 16 cases(72.73%) had a history of upper respiratory or other infections. The common features of histopathology were liquefaction degeneration of basal cells to varying degrees and perivasculitis of superficial or deep dermis. All children were treated with combination therapy, including systemic use of immunoglobulin, glucocorticoid, compound glycyrrhizin, erythromycin, etc, combined with topical drugs. 20 children(90.91%) were cured.

关 键 词：急性痘疮样苔藓样糠疹 儿童 组织病理 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]