谷氏验方治疗糖尿病足湿毒热盛证的疗效观察  

Therapeutic effects of GU’s empirical formula on diabetic foot of damp toxin and exuberant heat pattern

作　　者：贺智军 邓泽虎 谷井文 陈康清 资小明 陈祥 谢小艳 HE Zhijun;DENG Zehu;GU Jingwen;CHEN Kangqing;ZI Xiaoming;CHEN Xiang;XIE Xiaoyan(Leiyang Hospital of Chinese Medicine,Leiyang,Hunan 421800,China)

机构地区：[1]耒阳市中医医院,湖南耒阳421800

出　　处：《湖南中医药大学学报》2023年第2期294-298,共5页Journal of Hunan University of Chinese Medicine

基　　金：湖南省中医药科研计划项目(2020035)。

摘　　要：目的 研究谷氏验方治疗糖尿病足湿毒热盛证的临床疗效。方法 选取2019年6月至2021年9月于耒阳市中医医院普外科进行治疗的90例糖尿病足患者,采用随机数字表法分为观察组、对照组,每组45例。对照组接受常规西医清创、调控血糖、控制感染等基础治疗,观察组在对照组基础上联用谷氏验方,两组疗程均为1个月。比较两组患者治疗前后的糖代谢指标(空腹血糖、餐后血糖、糖化血红蛋白)、中医证候积分、下肢血管彩色多普勒超声检查积分及临床疗效。结果 治疗后,对照组糖化血红蛋白、中医证候积分、下肢血管彩色多普勒超声检查积分均明显低于治疗前(P<0.05);观察组空腹血糖、餐后血糖、糖化血红蛋白、中医证候积分、下肢血管彩色多普勒超声检查积分均明显低于治疗前(P<0.05),且均明显低于对照组(P<0.05);观察组总有效率95.35%,明显高于对照组的62.79%(P<0.01)。结论 谷氏验方能有效地治疗糖尿病足湿毒热盛证,改善患者的临床症状及糖代谢指标。Objective To study the therapeutic effects of GU’s empirical formula on diabetic of damp toxin and exuberant heat pattern. Methods A total of 90 patients with diabetic foot who were treated in the General Surgery Department of the Leiyang Hospital of Chinese Medicine from June 2019 to September 2021 were selected as the research objects.According to the random number table method, they were divided into two groups, observation group and control group, with45 cases in each group. The control group was treated with conventional western medicine debridement, blood glucose regulation, infection control and other basic treatment, and observation group was treated with combined GU’s empirical formula on the basis of control group. The treatment course of both groups was 1 month. Glucose metabolism indices(including fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin), TCM pattern score, lower limb Doppler ultrasonography score and clinical efficacy were compared between the two groups before and after treatment. Results After treatment, the glycosylated hemoglobin, TCM pattern score, lower limb Doppler ultrasonography score in the control group were significantly lower than those before treatment(P<0.05);the fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, TCM pattern score, lower limb Doppler ultrason ography score in the observation group were significantly lower than those before treatment(P <0.05), and were significantly lower than those in the control group(P <0.05);the total effective rate of the observation group(95.35%) was higher than that of the control group(62.79%)(P<0.01). Conclusion GU’s empirical formula can effectively treat diabetic foot of damp toxin and exuberant heat pattern, and improve the clinical symptoms and glucose metabolism indices.

关 键 词：糖尿病足 湿毒热盛证 谷氏验方 临床观察 血糖 中医证候积分 

分 类 号：R261[医药卫生—中医外科学]