松针化学成分、药理作用及其临床应用研究进展  

Research progress on chemical constituents,pharmacological effects and clinical application of pine needles

作　　者：陈子聿 乔小涵 陈金鹏 盖晓红[2,3,4] 刘毅 任涛[2,3,4] 田成旺 CHEN Zi-yu;QIAO Xiao-han;CHEN Jin-peng;GAI Xiao-hong;LIU Yi;REN Tao;TIAN Cheng-wang(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Tianjin Institute of Pharmaceutical Research,Tianjin 300462,China;Tianjin Key Laboratory of Quality Marker of Traditional Medicine,Tianjin 300462,China;State Key Laboratory of Drug Delivery and Pharmacokinetics,Tianjin 300462,China)

机构地区：[1]天津中医药大学,天津301617 [2]天津药物研究院,天津300462 [3]天津市中药质量标志物重点实验室,天津300462 [4]释药技术与药代动力学国家重点实验室,天津300462

出　　处：《中草药》2022年第24期7941-7954,共14页Chinese Traditional and Herbal Drugs

基　　金：中医药国际合作专项(0610-2140NF020630)。

摘　　要：松针作为一种传统中药,应用历史悠久,具有祛风燥湿、杀虫止痒等功效。松针为松科植物如马尾松Pinus massoniana、油松P.tabuliformis、红松P.koraiensis等的针状叶。松针中含有萜类、黄酮类、木脂素类、糖类等多种化学成分,具有抗氧化、降血糖、调血脂、抗肿瘤、抗菌、抗病毒等药理作用。基于近年的文献报道,对松针化学成分、药理作用及临床应用进行整理和总结,为松针的深入研究和开发利用提供参考。As a kind of traditional Chinese medicine,pine needles have a long history of application and have the effect of dispelling wind,dryness and dampness,killing insects and relieving itching.Pine needles are needle-like leaves of many varieties of Pinaceae,such as Pinus massoniana,P.tabuliformis,P.koraiensis and so on.Pine needles contain many kinds of chemical constituents,such as terpenoids,flavonoids,lignans,sugars and so on,which have the pharmacological effects of anti-oxidation,reducing blood sugar,regulating blood lipid,anti-tumor,anti-bacteria,anti-virus and so on.Based on recent literature reports,the chemical constituents,pharmacological effects and clinical application of pine needles are collated and summarized to provide reference for in-depth research,development and utilization of pine needles.

关 键 词：松针 萜类 黄酮类 抗氧化 抗肿瘤 临床应用 

分 类 号：R282.710.5[医药卫生—中药学]