Elsinochrome A photosensitizers:Alternative drugs for photodynamic therapy  

作　　者：Tinghui Li Hong Deng Jingquan Zhao Ying Gu 

机构地区：[1]Department of Laser Medicine,Chinese PLA General Hospital,Beijing 100853 People's Republic of China [2]Department of Dermatology,309 Hospital of PLA,Beijing 100091,People's Republic of China [3]Beijing National Laboratory for Molecular Sciences(BNLMS),Key Laboratory of Photochemistry,Institute of Chemistry Chinese Academy of Sciences,Beijing 100190 People's Republic of China

出　　处：《Journal of Innovative Optical Health Sciences》2015年第1期4-13,共10页创新光学健康科学杂志（英文）

基　　金：supported by the National Natural Science Foundation of China No.21303223.

摘　　要：Photodynamic therapy(PDT)has already been a multifunctional modality for various tumors and nontumorous diseases.However,the development of photosensitizers is relatively delayed,compared with the tremendous progress in laser technology.Elsinochrome A(EA),a per-ylenequinonoid pigment from China,has all the typical advantages of perylenequinones.More-over,singlet oxygen quantum yield of EA is superior to other kinds of photosensitizers and EA could be artifially biosynthesized at present,which make it an alternative candidate for PDT.In.this review,the photophysics,photochemistry,photobiology and chemical or biological syntheses of EA photosensitizers are brielty presented.Besides,the future prospects of EA photosensitizers are also proposed.

关 键 词：Elsinochrome A photodynamic therapy potochemisty PHOTOPHYSICS PHOTOBIOLOGY 

分 类 号：O62[理学—有机化学]