GlyCosmos门户网站在聚糖科学研究中的功能概述  

An Overview of The Functions of The GlyCosmos Portal in Glycosciences Research

作　　者：吉腾桤 张继[1,2] JI Teng-Qi;ZHANG Ji(Life Science College of Northwest Normal University,Lanzhou 730070,China;New Rural Development Research College of Northwest Normal University,Lanzhou 730070,China)

机构地区：[1]西北师范大学生命科学学院,兰州730070 [2]西北师范大学新农村发展研究院,兰州730070

出　　处：《生物化学与生物物理进展》2022年第12期2463-2468,共6页Progress In Biochemistry and Biophysics

基　　金：国家自然科学基金(51873175)资助项目。

摘　　要：近年来生物学领域的研究不断达到新高度,聚糖逐渐吸引越来越多科学家的目光,很多研究表明聚糖具有多种生物活性,越来越多的相关科研人员开始关注聚糖在生命过程中的作用及其机制。糖生物学逐渐成为生物学领域的热点学科。对于拟从事糖生物学研究或者刚进入该领域的新人来说,GlyCosmos作为一种全面的、统一的糖科学开放门户网站,其数据免费向大众公开,提供了对聚糖相关数据的访问,包括存储库,糖原、糖蛋白、信号通路和疾病相关的各种数据库及Glycome多种可视化数据库,目前最为前沿和统一的多种标准化多糖表示方法及其他多种功能。该网站是近两年才建成,但目前已被广泛使用也被糖生物学家所熟知。本文就GlyCosmos门户网站中的各项功能进行概述,希望帮助拟从事糖生物学研究的新人更好地了解和利用该网站,对于该网站的学习和理解,会对后续从事聚糖相关研究的研究者起到极大的帮助作用,也使后续研究更加便捷。As research in various fields of biology has reached new heights in recent years,glycans have gradually attracted the attention of scientists.Many studies have shown that glycans have multiple activities,which has caused more and more relevant researchers to pay attention to the role of sugar in life and how sugar works.Glycobiology has become a hot research area in biology.It is very important to have a good tool for newcomers to glycobiology research or just entering the field.GlyCosmos,as a comprehensive and unified open portal for glycoscience,whose data is freely available to the public,provides access to glycan-related data,including the following:(1)repository;(2)various databases related to glycogen,glyco proteins,cell pathways and diseases and various visualization databases of Glycome;(3)the most advanced and unified multiple standardized polysaccharide representation methods and other functions.Although the website has only been completed in the past two years,due to the convenience,uniformity and standardized model provided by the website,it has provided a standardized database and representation method for many international glycan studies,so the website has been widely used at present.The use is also well known by glycobiologists,so this website is very helpful for newcomers to glycobiology research.This article summarizes the functions in the GlyCosmos portal,hoping to help those who intend to engage in glycobiology to better understand and use the website,which will be helpful and provide reference value for subsequent research.

关 键 词：糖生物学 GlyCosmos 数据库 

分 类 号：Q539.7[生物学—生物化学]