厌氧消化对污泥中抗生素抗性基因削减的影响  

EFFECT OF SLUDGE ANAEROBIC DIGESTION ON THE REDUCTION OF ANTIBIOTIC RESISTANCE GENES

作　　者：向银萍 熊炜平 张燕茹 贾美莹 彭海豪 杨朝晖[1,2] XIANG Yinping;XIONG Weiping;ZHANG Yanru;JIA Meiying;PENG Haihao;YANG Zhaohui(College of Environmental Science and Engineering,Hunan University,Changsha 410082,China;Key Laboratory of Environmental Biology and Pollution Control(Hunan University),Ministry of Education,Changsha 410082,China;State Key Laboratory of Utilization of Woody Oil Resource,Hunan Academy of Forestry,Changsha 410004,China)

机构地区：[1]湖南大学环境科学与工程学院,长沙410082 [2]环境生物与控制教育部重点实验室(湖南大学),长沙410082 [3]湖南省林业科学院省部共建木本油料资源利用国家重点实验室,长沙410004

出　　处：《环境工程》2022年第10期192-202,241,共12页Environmental Engineering

基　　金：国家自然科学基金(51848258);湖南省创新型省份建设专项资金(2021SK2040);湖南省科技创新计划(2021RC2100)。

摘　　要：为了系统地了解厌氧消化及其强化工艺对污泥中抗生素抗性基因的削减效果,明确抗性基因在厌氧消化过程中的降解机制,从几种常见的厌氧消化工艺入手,结合国内外研究进展,综述了高温厌氧消化、预处理和投加外源添加剂等强化工艺对污泥中不同抗生素抗性基因的削减效果和影响因素,发现污泥中抗生素抗性基因的归趋主要与污泥中选择性压力的大小、宿主菌群的丰度、水平转移的效率和抗性基因的耐药机制等有关。厌氧消化及其强化工艺主要通过破坏污泥细胞结构,减少宿主菌群丰度或降低抗性基因水平转移风险的作用机制来实现抗生素抗性基因的高效削减。In order to systematically understand the removal efficiency of antibiotic resistance genes(ARGs) in sludge during anaerobic digestion and clarify the degradation mechanism of antibiotic resistance genes,this paper reviewed the effects of several common anaerobic digestion intensification processes,such as thermophilic anaerobic digestion,pretreatment technologies and additives injection on ARGs removal,taking the global research progress into account.It was found that the fate of ARGs was mainly related to the selective pressure in the sludge,the abundance of the host bacteria,the efficiency of horizontal gene transfer and the resistance mechanism of ARGs.Anaerobic digestion and its intensification processes mainly achieved an efficient reduction of ARGs by destroying the sludge cell structure,reducing the abundance of host bacteria and reducing the risk of horizontal gene transfer.

关 键 词：污泥 抗生素抗性基因 厌氧消化 宿主菌群 水平基因转移 

分 类 号：X703[环境科学与工程—环境工程] X172