不同赋形剂调制大黄粉干预肿瘤患者化疗后实性便秘的临床研究  

Clinical research on rhubarb powder modulated by different excipients to intervene solid constipation in cancer patients undergoing chemotherapy

作　　者：王坤[1] 侯燕丽 渠红[2] 宋志强 赵志正[1,2] Wang Kun;Hou Yanli;Ju Hong;Song Zhiqiang;Zhao Zhizhen(Department of Oncology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Department of Oncology,Xinjiang Production and Construction Corps Hospital,Urumchi 830092,China)

机构地区：[1]中国中医科学院广安门医院肿瘤科,北京100053 [2]新疆生产建设兵团医院肿瘤科,乌鲁木齐830092

出　　处：《中华现代护理杂志》2022年第35期4954-4958,共5页Chinese Journal of Modern Nursing

基　　金：国家中医临床研究示范基地科研专项暨所级科研基金(2017-S-406)。

摘　　要：目的探讨不同赋形剂调和大黄粉干预肿瘤患者化疗后符合中医实性便秘的效果。方法采用便利抽样法,选择中国中医科学院广安门医院肿瘤科2019年5月—2021年5月住院期间行化疗后发生实性便秘的120例肿瘤患者,采用随机数字表法分为观察组与对照组,每组60例。在常规治疗护理方案的基础上,对照组采用开塞露调和大黄粉穴位贴敷,观察组采用香油调和大黄粉穴位贴敷。比较两组的治疗有效率、便秘评分量表积分(CCS)、不良反应发生率。结果干预后,观察组的总有效率高于对照组,CCS评分、不良反应发生率低于对照组,以上差异均有统计学意义(P<0.05)。结论香油调制大黄进行穴位贴敷较开塞露调制可以更好地缓解化疗引起的便秘,且不良反应率低。Objective To explore the effects of dfferent excipients and rhubarb powder in interfering with TCM solid constipation in cancer patients undergoing chemotherapy.Methods Totally 120 tumor patients who developed solid constipation after chemotherapy during hospitalization from May 2019 to May 2021 in the Department of Oncology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences by convenience sampling and divided into an observation group and a control group according to the random number table,with 60 cases in each group.On the basis of the routine treatment and nursing protocol,patients in the control group received acupoint sticking with Kaisailu and rhubarb powder,and patients in the observation group were treated with sesame oil and rhubarb powder for acupoint sticking.The effective rate of treatment,the score of Cleveland Constipation Score(CCS),and the incidence of adverse reactions were compared between the two groups.Results After the intervention,the total effective rate in the observation group was higher than in the control group,the CCS score and the incidence of adverse reactions were lower than those of the control group,with statistically significant differences(P<0.05).Conclusions Acupoint sticking of rhubarb prepared with sesame oil can better relieve chemotherapy-induced constipation than that prepared with Kaisailu,and the adverse reactions rate is low.

关 键 词：肿瘤 大黄 便秘 赋形剂 穴位贴敷 开塞露 香油 

分 类 号：R248.9[医药卫生—中医临床基础]