米索前列醇联合利多卡因在绝经期取器中的效果  

Effect of misoprostol combined with lidocaine for intrauterine device removal of menopausal women

作　　者：高翠玲 周冰[2] 张华 李丽红 GAO Cuiling;ZHOU Bing;ZHANG Hua;LI Lihong(Qiongshan District Maternal and Child Health Care Hospital,Haikou,Hainan Province,571100;Haikou Maternal and Child Health Care Hospital;Hainan Women and Children Medical Center)

机构地区：[1]海南省海口市琼山区妇幼保健院,571100 [2]海南省海口市妇幼保健院 [3]海南省妇女儿童医学中心

出　　处：《中国计划生育学杂志》2023年第2期268-271,共4页Chinese Journal of Family Planning

基　　金：海南省自然科学基金资助(814382)。

摘　　要：目的:探讨米索前列醇联合利多卡因应用在绝经期取宫内节育器(IUD)对手术时间、疼痛程度和取器成功率的影响。方法:选取2020年1月-2022年1月于本院取器92例绝经期妇女,随机分为联合组(n=46)和单药组(n=46),均行IUD取器术,单药组于术前3小时阴道应用米索前列醇,联合组于术中应用米索前列醇联合利多卡因宫颈旁阴滞麻醉。比较两组术中情况(手术时间、术中出血量、术中疼痛程度)、宫颈软化程度、取器成功率以及用药安全性。结果:联合组手术时间(4.93±0.87 min)、术中出血量(3.62±0.65 ml)、术中疼痛视觉模拟评分(1.99±0.43分)均低于单药组(7.54±1.02 min、7.01±1.10 ml、5.17±0.90分),宫颈成功软化率(93.5%)及取器成功率(97.8%)均高于单药组(78.3%、87.0%)(均P<0.05);两组药物不良反应发生率(10.9%、6.5%)(P>0.05)。结论:米索前列醇联合利多卡因用于绝经期取器,能提升宫颈软化程度,减少术中出血量,缩短手术时间,提高取器成功率,缓解受术者术中疼痛,安全性较好。Objective: To explore the influence of misoprostol combined with lidocaine used in the intrauterine device(IUD) removal of menopausal women on their operation time, the pain degree, and the success rate of IUD removal. Methods: A total of 92 menopausal women who wanted IUD removal in the hospital were enrolled and were randomly divided into group A(46 women with misoprostol combined with lidocaine used during IUD removal) and group B(46 women with misoprostol used alone during IUD removal) between January 2020 and January 2022. The intraoperative conditions(operation time, intraoperative blood loss, and intraoperative pain), the degree of cervical softening, the success rate of IUD removal, and the medication safety of the women were compared between the two groups. Results: The operative time(4.93±0.87 min), the intraoperative blood loss(3.62±0.65 ml), and the intraoperative pain visual analog score(1.99±0.43 points) of the women in group A were all significantly lower than those(7.54±1.02 min, 7.01±1.10 ml, and 5.17±0.90 points) of the women in group B. The rate of successful cervical softening(93.5%) and the success rate of IUD removal(97.8%) of the women in group A were significantly higher than those(78.3% and 87.0%) of the women in group B(all P<0.05). There was no significant difference in the incidence of adverse drug reaction(10.9% vs. 6.5%) of the women between the two groups(P>0.05). Conclusion: The application of misoprostol combined with lidocaine for IUD removal of the menopausal women can improve their cervical softening, reduce their intraoperative blood loss, shorten their operation time, increase their success rate of IUD removal, and can greatly relieve their intraoperative pain, with better safety.

关 键 词：宫内节育器 绝经期取器 米索前列醇 利多卡因 手术时间 疼痛 取器成功率 

分 类 号：R614[医药卫生—麻醉学]