2-Methoxyjuglone, a Promising Bioactive Compound for Pharmaceutical and Agricultural Purposes: A Review  

作　　者：Heng-yi YU Lin LIU Juan LI Dong LIU Han-li RUAN 

机构地区：[1]Department of Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430030,China [2]School of Pharmacy,Tongji Medical College,Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation,Huazhong University of Science and Technology,Wuhan,430030,China

出　　处：《Current Medical Science》2022年第5期905-912,共8页当代医学科学（英文）

基　　金：supported by the National Natural Science Foundation of China(No.21572073 and No.3150010539).

摘　　要：2-Methoxyjuglone,a member of the 1,4-naphthoquinone family,was first obtained through semi-synthesis based on 2-hydroxyjuglone as the precursor in 1966.It has been isolated and identified from different plant species of the Juglandaceae,Sterculiaceae,and Proteaceae families.2-Methoxyjuglone has been demonstrated to possess a wide range of biological activities,including antitumor,antifungal,and antibacterial activities;in addition,it has been shown to poison fish and inhibit seed germination.These properties make 2-methoxyjuglone a promising bioactive compound for pharmaceutical and agricultural purposes.This review article provides an overview of the current research progress on 2-methoxyjuglone for the first time,with a primary focus on the plant sources,extraction,identification,synthesis,and biological activities associated with this compound for further development.

关 键 词：2-methoxyjuglone BIOACTIVITIES plant sources synthesis REVIEW 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]