个性化3D打印钛合金短柄股骨假体的生物力学评价  

Biomechanical Evaluation of Individualized 3D Printed Titanium Alloy Short Femoral Stem Prosthesis

作　　者：张润泽 刘宏伟 张文[3] 王佳峰 邵龙辉 王庆 蒋俊锋 王彩梅 ZHANG Runze;LIU Hongwei;ZHANG Wen;WANG Jiafeng;SHAO Longhui;WANG Qing;JIANG Junfeng;WANG Caimei(Graduate School,Dalian Medical University,Dalian 116044,Liaoning,China;Changzhou Second People's Hospital Affiliated to Nanjing Medical University Orthopaedics,Changzhou 213003,Jiangsu,China;Institute of Orthopaedics,Soochow University,Suzhou 215006,Jiangsu,China;Institute of Internet of Things Engineering,Hehai University,Changzhou 213022,Jiangsu,China;Beijing AK Medical Co.,Ltd.,Beijing 102200,China)

机构地区：[1]大连医科大学研究生院,辽宁大连116044 [2]南京医科大学附属常州第二人民医院骨科,江苏常州213003 [3]苏州大学骨科研究所,江苏苏州215006 [4]河海大学物联网工程学院,江苏常州213022 [5]北京爱康宜诚股份有限公司,北京102200

出　　处：《医用生物力学》2022年第6期1064-1069,共6页Journal of Medical Biomechanics

基　　金：国家自然科学基金项目(61772172);常州市卫健委重大项目(ZD201617)。

摘　　要：目的 评估个性化3D钛合金打印短柄股骨假体的生物力学性能。方法 采用4种不同的短柄股骨假体:3D打印1组(假体A)、3D打印2组(假体B)、BE组(假体C)、SMF组(假体D),分别对12根成人尸体股骨标本实行人工股骨头置换。在万能材料力学试验机上通过初始稳定性测试和静力压缩测试,对比分析4组假体模型变形量、最大压缩载荷、最大压缩位移和抗压缩刚度。结果 初始稳定性测试结果显示,3D打印2组假体变形量略低于3D打印1组,而明显低于SMF组和BE组,但差异无统计学意义(P>0.05)。3D打印2组假体最大压缩载荷、抗压缩刚度均大于其余3组,最大压缩位移小于其余3组,差异仍无统计学意义(P>0.05)。结论 个性化3D打印钛合金短柄股骨假体力学性能与目前临床常用的股骨SMF、BE 1假体相当,力学稳定性较好。Objective To evaluate the biomechanical strength of individualized three-dimensional(3D) titanium alloy short femoral stem prosthesis. Methods A total of 12 adult cadaveric femur specimens were treated with artificial femoral head replacement with 4 kinds of short femoral stem prostheses: 3D printing group 1(prosthesis A), 3D printing group 2(prosthesis B), BE 1(prosthesis C) and SMF(prosthesis D).The deformation, maximum compressive load, maximum compressive displacement and compressive stiffness of the four prosthesis models were compared and analyzed through initial stability test and static compression test on the universal material mechanics testing machine. Results The initial stability test results showed that the deformation of 3D printing group 1 was slightly lower than that of 3D printing group 2, and the deformation of 3D printing group 1 was significantly lower than that of SMF group and BE group, but the difference was not statistically significant(P>0.05). The maximum compressive load and compressive stiffness of 3D printing group 1 were higher than those of the other three groups, and the maximum compressive displacement was lower than that of the other three groups, but the difference was not statistically significant(P>0.05). Conclusions The mechanical properties of individualized 3D printing titanium alloy short femoral stem prosthesis are similar to those of SMF and BE 1 prosthesis that are used frequently in clinic, and its mechanical stability is good.

关 键 词：人工髋关节置换术 股骨假体 3D打印 个性化 力学测试 

分 类 号：R318.01[医药卫生—生物医学工程]