心脏康复训练对急性心肌梗死患者PCI术后心功能及血清炎症因子的影响  

Effect of Cardiac Rehabilitation Training on Cardiac Function and Serum Inflammatory Factors in Patients with Acute Myocardial Infarction after PCI

作　　者：韦颖[1] 莫昌干[1] 韦利元[1] 贝晓娜 赖冬艳 唐秀革[1] WEI Ying;MO Changgan;WEI Liyuan;BEI Xiaona;LAI Dongyan;TANG Xiuge(The People's Hospital of Hechi,Guangxi,Hechi 547000,China;不详)

机构地区：[1]广西河池市人民医院,广西河池547000

出　　处：《中国医学创新》2023年第3期53-56,共4页Medical Innovation of China

基　　金：河池重点研发计划项目(河科AB200724)。

摘　　要：目的:探讨心脏康复训练对急性心肌梗死(AMI)患者经皮冠状动脉介入治疗(PCI)术后心功能及血清炎症因子的影响。方法:选取2020年6月-2021年6月河池市人民医院心内科收治的100例行PCI术的AMI患者并随机分为观察组和对照组,各50例。对照组采用常规治疗和训练,观察组在对照组基础上联合心脏康复训练。比较两组心功能指标[左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)、左室射血分数(LVEF)]、血清炎症因子[C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)及白介素-6(IL-6)]及不良事件发生率。结果:治疗后,观察组LVESD、LVEDD较对照组均显著降低,LVEF较对照组显著增高(P<0.05);治疗后,观察组CRP、TNF-α、IL-6水平较对照组均显著降低(P<0.05);观察组不良事件发生率低于对照组(P<0.05)。结论:心脏康复训练有助于改善AMI患者PCI术后心功能,抑制机体炎症反应,降低不良事件发生风险。Objective: To explore the effect of cardiac rehabilitation training on cardiac function and serum inflammatory factors in patients with acute myocardial infarction(AMI) after percutaneous coronary intervention(PCI). Method: A total of 100 AMI patients undergoing PCI in the Department of Cardiology, the People’s Hospital of Hechi from June 2020 to June 2021 were selected and randomly divided into an observation group and a control group, 50 cases in each group. The control group was given routine treatment and training, and the observation group was given cardiac rehabilitation training on the basis of the control group. The cardiac function indexes [left ventricular end systolic diameter(LVESD), left ventricular end diastolic diameter(LVEDD) and left ventricular ejection fraction(LVEF)], serum inflammatory factors [C reactive protein(CRP), tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)] and the incidence of adverse events were compared between the two groups. Result: After treatment, the LVESD and LVEDD in the observation group were significantly lower than those in the control group,and LVEF was significantly higher than that in the control group(P<0.05). After treatment, the levels of CRP,TNF-α and IL-6 in the observation group were significantly lower than those in the control group(P<0.05).The incidence of adverse events in the observation group was lower than that in the control group(P<0.05).Conclusion: Cardiac rehabilitation training can improve cardiac function, inhibit inflammation reaction of body and reduce risk of adverse events in patients with AMI after PCI.

关 键 词：心脏康复训练 急性心肌梗死 经皮冠状动脉介入治疗 心功能 炎症因子 

分 类 号：R542.22[医药卫生—心血管疾病] R493[医药卫生—内科学]