聚焦式低强度脉冲超声波在膝骨关节炎治疗中的应用研究进展  

Research progress of focused low-intensity pulsed ultrasound in the treatment of knee osteoarthritis

作　　者：李远超 赵冰冰 杨畅然 罗庆禄 LI Yuanchao;ZHAO Bingbing;YANG Changran;LUO Qinglu(The Fifth Clinical College of Guangzhou Medical University,Guangzhou,Guangdong 510700,P.R.China;Clinical Medical College of Acupuncture Moxibustion and Rehabilitation,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 511400,P.R.China;Department of Rehabilitation,the Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510700,P.R.China)

机构地区：[1]广州医科大学第五临床学院,广州510700 [2]广州中医药大学针灸康复临床医学院,广州511400 [3]广州医科大学附属第五医院康复医学科,广州510700

出　　处：《华西医学》2023年第1期134-139,共6页West China Medical Journal

基　　金：国家自然科学基金(82072544)。

摘　　要：聚焦式低强度脉冲超声波(focused low-intensity pulsed ultrasound,FLIPUS)作为一种无创的物理治疗方法,广泛应用于骨科、神经外科、泌尿外科和康复医学科等临床专科。越来越多的研究发现FLIPUS可以通过促进组织再生、缓解疼痛与抑制炎症等机制来治疗膝骨关节炎(knee osteoarthritis,KOA),改善KOA的常见临床症状,如关节疼痛或僵硬、关节活动受限和步行功能下降,且能在一定程度上提高患者的生活质量。该文主要就FLIPUS治疗KOA的作用和生物物理机制以及相关临床研究作一综述,旨在为开展这方面研究的临床工作者提供参考。Focused low-intensity pulsed ultrasound(FLIPUS),as a non-invasive physical therapy,is widely used in orthopedics,neurosurgery,urology,rehabilitation medicine and other clinical specialties.More and more studies have found that FLIPUS can treat knee osteoarthritis(KOA)by promoting tissue regeneration,relieving pain and inhibiting inflammation,improve the common clinical symptoms of KOA,such as joint pain or stiffness,limited joint activity and decreased walking function,and improve the quality of life of patients to a certain extent.This article mainly reviews the effect and biophysical mechanism of FLIPUS in the treatment of KOA,as well as related clinical research,in order to provide a reference for clinical workers who carry out research in this field.

关 键 词：超声波 低强度超声波 聚焦式低强度脉冲超声波 膝骨关节炎 

分 类 号：R684.3[医药卫生—骨科学]