基于2-甲酰基苯并噻唑与2-氨甲基吡啶串联合成四取代吡咯衍生物及其光学性质研究  

Domino Synthesis of Tetrasubstituted Pyrole Derivative from 2-Formylbenzothiazole and 2-Aminomethylpyridine and its Photophysical Property Study

作　　者：罗美莲 张蓝贝 Luo Meilian;Zhang Lanbei(College of Chemistry and Chemical Engineering,Hubei University,Wuhan 430062,China)

机构地区：[1]湖北大学化学化工学院,湖北武汉430062

出　　处：《广东化工》2023年第1期15-18,共4页Guangdong Chemical Industry

摘　　要：串联反应可以从简单原料经简单步骤直接获得结构复杂的化合物,具有很高的原子经济性。同时节省能源、人力、时间、及溶剂的使用,吸引了越来越多化学家的研究兴趣。本文利用2-甲酰基苯并噻唑(L1)和2-氨甲基吡啶(L2)在FeCl_(2)·4H_(2)O的存在下的溶解热反应,“一锅”串联合成了四苯并噻唑取代的吡咯衍生物3。化合物3经过X-射线单晶衍射和红外光谱表征,并且对光学性质进行了初步研究,发现其紫外-可见光谱的最大吸收峰分别在382 nm和413 nm,荧光发射光谱的最大发射波长在433 nm和515 nm。该工作表明,基于Fe^(2+)离子配位导向的杂芳基甲醛与杂芳基甲胺之间的串联反应,可以直接获得结构复杂且新颖的杂环聚集体,为有机合成等领域提供新的研究对象且具有潜在的应用价值。Domino reactions are attracting more and more research interest from chemists because of their atomic,energy,labor,solvent and time economy.2-formylbenzothiazole(L1)and picolinylamine(L2)generated tetrasubstituted pyrole derivative 3 in the presence of FeCl_(2)·4H_(2)O.Compound 3 was characterized by X-ray single crystal diffraction.The optical properties of the 3 showed that in UV-Vis spectrum the maximum absorption wavelengthes were at 382 nm and 413 nm,respectively.The maximum emission wavelengths of the fluorescence emission spectrum are at 433 nm and 515 nm.This work shows that complex and novel heterocyclic aggregates can be directly obtained based on the domino reaction between Fe^(2+)ion coordination-directed heteroaryl formaldehyde and heteroaryl methylamine,providing a new research object for the fields of organic synthesis and so on and has potential application value.

关 键 词：溶剂热反应 串联反应 晶体学 荧光性质 

分 类 号：TQ[化学工程]