腹膜透析治疗慢性肾功能衰竭尿毒症的效果  

Effect of peritoneal dialysis on uremic due to chronic renal failure

作　　者：朱晓光 李雯雯 时军 Zhu Xiaoguang;Li Wenwen;Shi Jun(Department of Nephrology,Huaihe Hospital of Henan University,Kaifeng 475000,China;Department of Cardiology,Huaihe Hospital of Henan University,Kaifeng 475000,China)

机构地区：[1]河南大学淮河医院肾内科,开封475000 [2]河南大学淮河医院心内科,开封475000

出　　处：《中国实用医刊》2022年第21期53-56,共4页Chinese Journal of Practical Medicine

摘　　要：目的探讨腹膜透析治疗慢性肾功能衰竭尿毒症的临床效果。方法抽取2018年9月至2020年9月河南大学淮河医院收治的慢性肾功能衰竭尿毒症患者82例,按随机数字表法分为腹膜透析组与血液透析组,每组41例。血液透析组采用血液透析治疗,腹膜透析组采用腹膜透析治疗。比较两组治疗效果,白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、尿素氮(BUN)、血肌酐(Scr)、红细胞(RBC)、血红蛋白(Hb)水平及并发症发生率。结果治疗后,腹膜透析组总有效率(90.24%,37/41)高于血液透析组(73.17%,30/41),P<0.05。治疗后,腹膜透析组IL-6、TNF-α、BUN、Scr水平低于血液透析组(P<0.05);RBC、Hb水平高于血液透析组(P<0.05)。腹膜透析组并发症发生率(9.76%,4/41)与血液透析组(14.63%,6/41)比较差异未见统计学意义(P>0.05)。结论腹膜透析治疗慢性肾功能衰竭尿毒症可提高治疗效果,缓解炎症状态,改善肾功能,纠正营养状态,且具有安全性。Objective To investigate the clinical effect of peritoneal dialysis in the treatment of uremic due to chronic renal failure.Methods A total of 82 uremic patients due to chronic renal failure admitted to Huaihe Hospital of Henan University from September 2018 to September 2020 were selected,and they were divided into peritoneal dialysis group and hemodialysis group according to random number table method,with 41 cases in each group.The hemodialysis group was treated by hemodialysis,and the peritoneal dialysis group was treated by peritoneal dialysis.The therapeutic effects,levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),blood urea nitrogen(BUN),blood creatinine(Scr),red blood cell(RBC),hemoglobin(Hb)and incidence of complications were compared between the two groups.Results After treatment,the total effective rate of the peritoneal dialysis group(90.24%,37/41)was higher than that of the hemodialysis group(73.17%,30/41),P<0.05.After treatment,the IL-6,TNF-α,BUN and Scr levels in the peritoneal dialysis group were lower than those in the hemodialysis group(P<0.05);the levels of RBC and Hb in the peritoneal dialysis group were higher than those in the hemodialysis group(P<0.05).There was no significant difference in the complication rate between the peritoneal dialysis group(9.76%,4/41)and the hemodialysis group(14.63%,6/41),P>0.05.Conclusions Peritoneal dialysis in the treatment of chronic renal failure uremia can improve the treatment effect,alleviate inflammation,improve renal function,and correct nutritional status,with great safety.

关 键 词：尿毒症 慢性肾功能衰竭 腹膜透析 血液透析 

分 类 号：R692.5[医药卫生—泌尿科学]