海南省农村居民血脂异常和边缘升高状况及合并慢性疾病情况调查  

Investigation on dyslipidemia,elevated borderline lipid and corresponding complicated chronic diseases in rural residents of Hainan province

作　　者：欧倩滢[1] 林乐韦华[1] 林璐 方团育[1] 张华川[1] 陈开宁[1] 陈道雄[1] 全会标[1] OU Qianying;LIN Leweihua;LIN Lu(Department of Endocrinology,Hainan General Hospital/Hainan Affiliated Hospital of Hainan Medical University,Hainan,Haikou 570311,China;不详)

机构地区：[1]海南省人民医院、海南医学院附属海南医院内分泌科,海口市570311 [2]中国人民解放军总医院第一医学中心内分泌科

出　　处：《河北医药》2022年第24期3816-3819,共4页Hebei Medical Journal

基　　金：海南省临床医学中心建设项目资助项目(编号:琼卫医函[2021]276号);海南省重点研发计划项目(编号:ZDYF2018130);海南省卫生健康行业科研项目(编号:20A200198)。

摘　　要：目的了解海南省农村居民血脂异常和边缘升高及其合并其他慢性代谢性疾病的患病情况。方法采用多阶段分层整群随机抽样的方法选取2018至2020年海南省农村>18岁1120人为研究对象,对发生血脂异常和边缘升高的患病率、合并的其他慢性代谢性疾病的情况以及危险因素进行分析。结果海南省农村成人1120人,平均年龄(49.25±13.74)岁。其中男性389人,平均年龄(49.96±13.80)岁;女性731人,平均年龄(48.87±13.70)岁。少数民族151人,占13.5%。血脂代谢异常(包括血脂异常和边缘升高)的粗患病率75.98%,标化患病率71.87%。其中血脂异常的粗患病率43.75%,标化患病率40.59%;血脂边缘升高的粗患病率32.23%,标化患病率31.28%。血脂异常的人群中19.80%合并糖尿病,34.69%合并高血压,27.55%合并高尿酸血症,57.55%合并超重和肥胖,50.00%合并代谢综合征,患病率均高于血脂边缘升高人群(P<0.05)和正常水平血脂人群(P<0.01)。血脂边缘升高人群合并上述慢性病的患病率依次为11.08%、22.99%、21.33%、40.72%和25.48%,除了糖尿病,其他慢性病的患病率均高于正常水平血脂人群(P<0.01)。Logistic回归分析显示年龄、体重指数、高血压、糖尿病、高尿酸血症是海南省农村居民血脂异常的危险因素(P<0.05);年龄、体重指数、高尿酸血症是血脂边缘升高的危险因素(P<0.05)。结论海南省农村居民血脂代谢异常的患病率很高。在血脂边缘升高时,合并其他慢性代谢性疾病的患病率就已经明显升高。因此需要高度重视,通过避免超重/肥胖和治疗高尿酸血症提前预防血脂边缘升高的发生。Objective To understand the morbidity conditions of dyslipidemia,elevated borderline lipid and corresponding complicated chronic metabolic diseases in rural residents of Hainan province.Methods A total of 1120 people aged 18 years old or above in rural area of Hainan were selected as subjects of study by multistage stratified cluster random sampling method from 2018 to 2020,and the morbidity conditions of dyslipidemia and elevated borderline lipid and incidences of other chronic metabolic diseases and risk factors were analyzed.Results The crude morbidity rate of abnormal blood lipid metabolism(including dyslipidemia and elevated borderline lipid)in rural adults from Hainan was 75.98%,and the standardized morbidity was 71.87%.The crude morbidity of dyslipidemia was 43.75%,and the standardized morbidity rate was 40.59%.The crude morbidity of elevated borderline lipid was 32.23%,and the standardized morbidity was 31.28%.In the dyslipidemia patients,there were 19.80%patients complicated with diabetes mellitus,34.69%complicated with hypertension,27.55%patients complicated with hyperuricemia,57.55%patients complicated with overweight and obesity,50.00%patients complicated with metabolic syndrome,the morbidity rate of the diseases was higher than that of population with elevated borderline lipid(P<0.05)and appropriate serum lipid(P<0.01).In the elevated borderline lipid patients,the morbidity of patients with complicated diseases were 11.08%,22.99%,21.33%,40.72%and 25.48%respectively,the morbidity rate of other chronic diseases was higher than that of patients with appropriate serum lipid except diabetes(P<0.01).Logistic regression analysis showed that the age,body mass index(BMI),hypertension,diabetes and hyperuricemia were risk factors for dyslipidemia in rural residents of Hainan(P<0.05).The age,BMI and hyperuricemia were considered to be risk factors for the elevated borderline lipid(P<0.05).Conclusion The morbidity rate of rural residents with abnormal serum lipid in Hainan is extremely high.The morbidity rate of

关 键 词：血脂异常 患病率 危险因素 肥胖 高尿酸血症 

分 类 号：R195.4[医药卫生—卫生统计学]