^(18)F-FDG PET/CT心肌代谢图像质量评价的研究  

Evaluation of^(18)F-FDG PET/CT myocardial metabolism image quality

作　　者：张磊[1] 李肖红[1] 秦永德[1] 马婷[2] 阿米娜·依布拉音 娜姿·伊力哈木 Zhang Lei;Li Xiaohong;Qin Yongde;Ma Ting;Amina Yibulayin;Nazi Yilihamu(Department of Nuclear Medicine,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China;Department of Cardiac Ultrasound,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China)

机构地区：[1]新疆医科大学第一附属医院核医学科,乌鲁木齐830000 [2]新疆医科大学第一附属医院心脏超声科,乌鲁木齐830000

出　　处：《中国医师杂志》2023年第1期43-46,共4页Journal of Chinese Physician

基　　金：省部共建中亚高发病成因与防治国家重点实验室开放课题(SKL-HIDCA-2017-Y13)。

摘　　要：目的探讨以左心室心肌与心血池最大标准摄取值的比值(M/B)评价^(18)F-FDG PET/CT心肌代谢图像质量的价值。方法回顾性选取2016年1月至2020年8月新疆医科大学第一附属医院收治的145例确诊冠心病的非糖尿病患者的临床资料,均静脉注射^(18)F-FDG进行心肌糖代谢显像。根据视觉(定性)分析将图像分为最佳、次优、较差三类。A组为图像最佳质量组,B组为图像次优和较差组。将左心室心肌、心血池、降主动脉^(18)F-FDG最大标准化摄取值(SUVmax)进行半定量分析,并计算M/B值。结果145例患者均进行了图像融合分析。图像视觉(定性)分析,111例患者的心肌代谢图像质量评估为最佳(A组111例),19例评估为次优,15例评估较差(B组34例)。两组降主动脉SUVmax值均小于左心室SUVmax值,差异有统计学意义(均P<0.05)。A组M/B值大于B组,差异有统计学意义(P<0.05)。结论对于评价图像质量及图像判读的可靠性而言,M/B值可能是一个较好的评价指标,减少了因部分心血池^(18)F-FDG高摄取对图像质量评价的干扰,提高了对心肌存活评价的准确性。Objective To evaluate the value of 18F-fluorodeoxyglucose positron emission computed tomography(18F-FDG PET/CT)myocardial metabolic image quality by the ratio of the maximum standard uptake value(M/B)of left ventricular myocardium to cardiac blood pool.Methods The clinical data of 145 non diabetes patients with coronary heart disease who were admitted to the First Affiliated Hospital of Xinjiang Medical University from January 2016 to August 2022 were retrospectively selected.All patients received intravenous injection of 18F-FDG for myocardial glucose metabolism imaging.According to the visual(qualitative)analysis,the image was divided into three categories:the best,the second best and the worst.Group A was the best image quality group,while Group B was the second best and the worst image quality group.The left ventricular myocardium,cardiac blood pool and descending aorta were semi-quantitatively analyzed,and M/B was calculated.Results All 145 patients underwent image fusion analysis.Image visual(qualitative)analysis showed that the myocardial metabolic image quality of 111 patients was evaluated as the best(111 patients in Group A),19 patients as the second best,and 15 patients as the worst(34 patients in Group B).The SUVmax value of the descending aorta in the two groups was lower than that of the left ventricle,with statistically significant difference(all P<0.05).The M/B value of group A was higher than that of group B,with statistically significant difference(P<0.05).Conclusions For the evaluation of image quality and the reliability of image interpretation,M/B value may be a good evaluation index,which reduces the interference of image quality evaluation due to high 18F-FDG uptake in some heart blood pools(background),and improves the accuracy of evaluation of myocardial viability.

关 键 词：氟脱氧葡萄糖F18 正电子发射断层显像计算机体层摄影术 左心室 心肌 

分 类 号：R541.4[医药卫生—心血管疾病]