^(18)F-FDG PET评估存活心肌指导冠状动脉血运重建治疗的研究进展  

Coronary Revascularization Therapy Guided by^(18)F-FDG PET in Evaluating Viable Myocardium

作　　者：韩旭[1] 汪蕾[1] 方纬[1] HAN Xu;WANG Lei;FANG Wei(Department of Nuclear Medicine,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China)

机构地区：[1]北京协和医学院、国家心血管病中心、中国医学科学院阜外医院核医学科,北京100037

出　　处：《心血管病学进展》2023年第1期11-15,共5页Advances in Cardiovascular Diseases

摘　　要：对于冠心病合并心功能障碍患者,心肌存活的评价对于血运重建治疗的决策具有重要意义。^(18)F-氟代脱氧葡萄糖正电子发射断层成像(^(18)F-FDG PET)心肌代谢显像被认为是检测存活心肌的“金标准”。现主要涉及两方面内容,一是^(18)F-FDG PET评估存活心肌用于指导血运重建治疗是否有助于预测患者左心室功能的恢复或改善;二是^(18)F-FDG PET评估存活心肌用于指导血运重建是否有助于改善患者的预后。现综述相关的临床研究进展,PARR-2和STICH两个重要的随机对照研究所引发的争议,以及这一领域未来的研究方向。For patients with coronary heart disease and cardiac dysfunction,the evaluation of viable myocardium is of great significance for the decision-making of revascularization therapy.^(18)F-fluorodeoxyglucose positron emission tomography(^(18)F-FDG PET)myocardial metabolism imaging is considered to be a“gold standard”for detecting viable myocardium.There are mainly two aspects involved.One is whether^(18)F-FDG PET is helpful to predict the recovery or improvement of left ventricular function in patients with viable myocardium to guide revascularization therapy;the other is whether^(18)F-FDG PET can improve the prognosis of patients by evaluating the viable myocardium to guide the revascularization.This article reviews the related clinical research progress,the controversy caused by two important randomized controlled studies(PARR-2 and STICH),and the future research direction in this field.

关 键 词：^(18)F-氟代脱氧葡萄糖正电子发射断层成像 冠心病 存活心肌 血运重建 

分 类 号：R541.4[医药卫生—心血管疾病]