心脏交感神经显像的临床应用和研究进展  

Clinical Application and Research Progress of Cardiac Sympathetic Imaging

作　　者：琚敏 汪蕾[1] 宋雷[2] 方纬[1] JU Min;WANG Lei;SONG Lei;FANG Wei(Department of Nuclear Medicine,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China;Department of Cardiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China)

机构地区：[1]北京协和医学院、国家心血管病中心、中国医学科学院阜外医院核医学科,北京100037 [2]北京协和医学院国家心血管病中心、中国医学科学院阜外医院心内科,北京100037

出　　处：《心血管病学进展》2023年第1期16-20,共5页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(81971654)

摘　　要：交感神经系统在调节心血管功能方面起着关键作用,其功能异常是多种心血管疾病发生和发展的重要机制。应用放射性核素心脏交感神经显像,可无创性评估心脏交感神经支配的功能状态和病理改变,在疾病诊断、危险分层、预后评估和疗效评价等方面都具有重要的作用。现综述心脏交感神经显像技术在心力衰竭、缺血性心脏病和心脏移植等方面的临床应用研究,以及研发新型显像药物对该技术普及推广的意义。Sympathetic nervous system plays a key role in regulating cardiovascular function,and its dysfunction is an important mechanism for the occurrence and development of many cardiovascular diseases.Radionuclide cardiac sympathetic imaging can non-invasively evaluate the functional state and pathological changes of cardiac sympathetic innervation,and it plays an important role in disease diagnosis,risk stratification,prognosis evaluation and curative effect evaluation.This article reviews the clinical application of cardiac sympathetic imaging technology in heart failure,ischemic heart disease and heart transplantation,and the significance of developing new imaging drugs for the popularization of this technology.

关 键 词：心脏交感神经 放射性核素显像 心力衰竭 缺血性心脏病 

分 类 号：R54[医药卫生—心血管疾病]