重复经颅磁刺激在脑性瘫痪儿童睡眠障碍中的应用效果  

Application effect of repetitive transcranial magnetic stimulation on sleep disorders in children with cerebral palsy

作　　者：易彩英 张峰 陈福建 朱美俊 刘诗贤 YI Caiying;ZHANG Feng;CHEN Fujian;ZHU Meijun;LIU Shixian(Department of Pediatric Neurological Rehabilitation,Ganzhou Maternal and Child Health Hospital,Jiangxi Province,Ganzhou341000,China)

机构地区：[1]江西省赣州市妇幼保健院儿童神经康复科,江西赣州341000

出　　处：《中国当代医药》2023年第5期118-121,125,共5页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(20204664)。

摘　　要：目的探讨重复经颅磁刺激(rTMS)在脑性瘫痪儿童睡眠障碍中的应用效果。方法选取2019年5月至2020年5月赣州市妇幼保健院儿童神经康复科的50例脑性瘫痪睡眠障碍儿童作为研究对象,发放随机信封,根据单双号分为观察组与对照组,各25例。对照组采用伪刺激治疗,观察组采用rTMS治疗。比较两组患儿治疗前后的儿童睡眠习惯问卷(CSHQ)、汉密尔顿抑郁量表(HAMD)睡眠障碍因子水平,并评估治疗效果。结果整体分析显示,CSHQ各项评分的组间比较、时间点比较及交互作用差异均有统计学意义(P<0.05)。进一步两两比较,观察组患儿治疗后12、16周的CSHQ各项评分均低于本组治疗前,差异有统计学意义(P<0.05);对照组患儿治疗后16周的CSHQ各项评分均低于本组治疗前,差异有统计学意义(P<0.05)。观察组患儿治疗后12、16周的CSHQ各项评分均低于对照组,差异有统计学意义(P<0.05)。两组患儿治疗后12、16周的HAMD睡眠障碍因子水平均低于本组治疗前,差异有统计学意义(P<0.05);两组患儿治疗后16周的HAMD睡眠障碍因子水平均低于本组治疗后12周,差异有统计学意义(P<0.05)。观察组患儿治疗后12、16周的HAMD睡眠障碍因子水平均低于对照组,差异有统计学意义(P<0.05);观察组患儿的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论将rTMS应用于脑性瘫痪儿童睡眠障碍治疗,其在改善患儿睡眠习惯及睡眠障碍方面有着突出效果,疗效可靠。Objective To explore the effect of repetitive transcranial magnetic stimulation(rTMS)on sleep disorders in children with cerebral palsy.Methods A total of 50 children with cerebral palsy and sleep disorder in Department of Pediatric Neurological Rehabilitation of Ganzhou Maternal and Child Health Hospital from May 2019 to May 2020 were selected as the research objects,and randomized envelopes were distributed,they were distributed into the observation group and the control group according to odd and even numbers,with 25 cases in each group.The control group was treated with pseudo stimulation,and the observation group was treated with rTMS.The sleep disorder factor levels of children's sleep habit questionnaire(CSHQ)and Hamilton depression scale(HAMD)were compared before and after treatment,and the treatment effect was evaluated.Results The overall analysis showed that there were statistically significant differences in the inter group comparison,time point comparison and interaction of CSHQ scores(P<0.05).Further comparison between the two groups showed that the CSHQ scores of the children in the observation group at 12 and 16 weeks after treatment were lower than those before treatment,with statistically significant difference(P<0.05).The CSHQ scores of children in the control group at 16 weeks after treatment were lower than those before treatment,and the differences were statistically significant(P<0.05).The CSHQ scores of children in the observation group at 12 and 16 weeks after treatment were lower than those in the control group,with statistically significant differences(P<0.05).The levels of HAMD sleep disorder factors in the two groups at 12 and 16 weeks after treatment were lower than those before treatment,and the differences were statistically significant(P<0.05).The levels of HAMD sleep disorder factors in the two groups at 16 weeks after treatment were lower than those at 12 weeks after treatment,and the differences were statistically significant(P<0.05).The levels of HAMD sleep disorder factors in

关 键 词：重复经颅磁刺激 脑性瘫痪 儿童睡眠障碍 儿童睡眠习惯问卷 汉密顿抑郁量表睡眠障碍因子 

分 类 号：R729[医药卫生—儿科]