2017—2021年江苏省土源性线虫感染情况监测分析  

Analysis of surveillance on soil-transmitted nematode infections in Jiangsu Province from 2017 to 2021

作　　者：倪碧娴 徐祥珍[1] 金小林[1] 丁昕 张强 茅范贞 戴洋[1,2] NI Bi-xian;XU Xiang-zhen;JIN Xiao-lin;DING Xin;ZHANG Qiang;MAO Fan-zhen;DAI Yang(Key Laboratory of Parasitic Disease Prevention and Control Technology of National Health Council,Key Laboratory of Parasite and Vector Control Technology of Jiangsu Province,Jiangsu Institute of Parasitic Diseases,Wuxi 214064,China;Global Health Center of Nanjing Medical University,Nanjing 211166,China)

机构地区：[1]国家卫生健康委员会寄生虫病预防和控制技术重点实验室,江苏省寄生虫与媒介控制技术重点实验室,江苏省血吸虫病防治研究所,无锡214064 [2]南京医科大学全球健康中心,南京211166

出　　处：《中国寄生虫学与寄生虫病杂志》2022年第6期730-736,共7页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：目的了解2017—2021年江苏省土源性线虫感染情况,为制定科学的防治策略提供依据。方法2017—2021年,江苏省每年选取8个县(市、区)作为监测点(固定监测点1个,每年不变;流动监测点7个,每年不同)。各监测点按照东、西、南、北、中等5个地理方位,每个方位抽取1个乡(镇)的1个行政村开展监测调查,每个行政村抽取3周岁以上常住居民不少于200人。采集监测对象粪样约30 g,通过改良加藤厚涂片法(Kato-Katz法,一粪二检)检测虫卵,计算各虫种感染率和感染度。钩虫阳性粪样再用试管滤纸培养法鉴定钩虫虫种。3~9周岁儿童加做透明胶纸肛拭法检测蛲虫感染情况。从固定监测点每村随机抽取5户住户,每户采集1份菜园或田地的土样(≥400 g),其中350 g土样用于钩蚴检测,50 g用于人蛔虫卵检测。感染率的比较采用卡方检验。结果2017—2021年江苏省累计调查41753人,土源性线虫总感染率为0.30%(124/41753)。蛔虫、钩虫、鞭虫和蛲虫的感染率分别为0.13%(56/41753)、0.06%(24/41753)、0.02%(10/41753)和0.08%(34/41753),所有土源性线虫感染者均为轻度感染。固定监测点土源性线虫总感染率为0.37%(21/5699),流动监测点为0.29%(103/36054),二者差异无统计学意义(χ^(2)=0.19,P>0.05)。2017—2021年,土源性线虫总感染率分别为0.26%(22/8549)、0.54%(46/8452)、0.22%(19/8454)、0.37%(30/8189)和0.09%(7/8109),不同年度间感染率差异有统计学意义(χ^(2)=32.88,P<0.01)。13个设区市中,土源性线虫总感染率最高的为连云港市(1.17%,48/4119),其次是宿迁市(0.38%,21/5487)和淮安市(0.36%,11/3040),不同设区市间感染率差异有统计学意义(χ^(2)=137.52,P<0.01)。男性土源性线虫总感染率为0.26%(52/19773),女性为0.33%(72/21980)(χ^(2)=1.47,P>0.05);3~9岁年龄组土源性线虫总感染率最高,为0.86%(35/4093),不同年龄组人群间感染率差异有统计学意义(χ^(2)=53.24,P<0.01);幼托儿童土源性线虫�Objective To understand the current status of soil-transmitted nematode infections in Jiangsu Province from 2017 to 2021,and provide the basis for the formulating scientific prevention and control strategies.Methods From 2017 to 2021,eight counties(cities,districts)in Jiangsu Province were selected as surveillance sites each year(one fixed site,and seven ambulatory sites changed on yearly base).The surveillance sites were randomly selected from five geographical sections in the east,west,south,north and centre,from each of which one township(town)was selected to set up surveillance site therein one administrative village.No less than 200permanent residents over the age of 3 in each administrative village were selected for surveillance.About 30 g of fecal sample was collected from each participant for examining nematode eggs using the modified Kato-Katz thick smear method(two slide-reading each sample),to calculate infection rate and intensity of different species..Hookworm-positive fecal samples were used to identify parasite species by test tube-filter paper culture method.Children aged 3 to 9 years old were additionally examined for Enterobius vermicularis infection by adhesive cellophane swabs method.Five households were randomly selected from each village at fixed surveillance site to collect soil sample(≥400 g)from vegetable garden or field of each household,of which 350 g were used for detection of hookworm eggs,and 50 g for Ascaris lumbricoides eggs.Infection rates were compared between groups using the chi-square test.Results From 2017 to 2021,a total of 41753 people were examined in Jiangsu Province surveillance sites,and found the overall infection rate of soil-transmitted nematodes at 0.30%(124/41753).The infection rates of A.lumbricoides,hookworm,Trichuris trichura and Enterubius vermicularis were 0.13%(56/41753),0.06%(24/41753),0.02%(10/41753)and 0.08%(34/41753)respectively,and all soil-transmitted nematode infections were of mild type.The infection rate of soil-transmitted nematodes at fixed monit

关 键 词：土源性线虫 感染 国家监测点 江苏省 

分 类 号：R383.1[医药卫生—医学寄生虫学]