超声引导下置管引流联合聚桂醇硬化与无水乙醇硬化治疗卵巢子宫内膜异位囊肿的价值比较  

Comparison of the Value of Ultrasound-guided Catheter Drainage Combined with Poly Cinnamol Sclerotherapy and Absolute Ethanol Sclerotherapy in the Treatment of Ovarian Endometrial Cysts

作　　者：陈华彬 邹斌 林勇平 张路生 陈文娟 李程 Chen Huabin;Zou Bin;Lin Yongping;Zhang Lusheng;Chen Wenjuan;Li Cheng(Department of Ultrasound,Zhongshan Hospital of Traditional Chinese Medicine(Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine),Zhongshan,Guangdong 528400)

机构地区：[1]中山市中医院(广州中医药大学附属中山中医院)超声科,广东中山528400

出　　处：《现代医用影像学》2022年第12期2202-2206,共5页Modern Medical Imageology

摘　　要：目的:比较超声引导下置管引流联合聚桂醇硬化与无水乙醇硬化治疗卵巢子宫内膜异位囊肿(OEC)的价值。方法:选取2017年9月至2021年9月于中山市中医院超声科行超声引导下硬化治疗OEC患者60例,根据随机数字表法将其分为参照组(n=30,35个囊肿)和观察组(n=30,38个囊肿),参照组患者采取超声引导下置管引流联合无水乙醇硬化治疗,观察组患者采取超声引导下置管引流联合聚桂醇硬化治疗。比较两组患者术后3个月、术后6个月的治疗总有效率;观察两组患者围术期不良反应;比较两组患者术前和术后3个月血清指标[糖类抗原125(CA125)、糖类抗原199(CA199)]、性激素[卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)]水平变化。结果:术后3个月和术后6个月,两组患者治疗总有效率差异无统计学意义(P>0.05);观察组患者腹痛、发热、醉酒样不良反应发生率显著低于参照组(P<0.05);术后3个月,两组患者血清CA125水平较术前均降低(P<0.05),且观察组低于参照组(P<0.05);两组患者血清CA199、FSH、LH、E2术前、术后间差异均无统计学意义(P>0.05)。结论:超声引导下置管引流联合聚桂醇硬化治疗或无水乙醇治疗OEC均能取得满意治疗效果,但采用聚桂醇硬化治疗围术期不良反应明显低于无水乙醇,该介入治疗方案安全有效,值得推广。Purpose:To compare the value of ultrasound-guided catheter drainage combined with cinnamyl alcohol sclerotherapy and absolute alcohol sclerotherapy in the treatment of ovarian endometrial cysts(OEC).Materials and Methods:From September 2017 to September 2021,60 patients with OEC were selected for ultrasound guided sclerotherapy in the Ultrasound Department of Zhongshan Hospital of Traditional Chinese Medicine,they were divided into the reference group(n=30,35 cysts)and the observation group(n=30,38 cysts)according to the random number table method,The patients in the reference group were treated with ultrasound guided catheter drainage combined with ethanol sclerotherapy,while the patients in the observation group were treated with ultrasound guided catheter drainage combined with cinnamyl alcohol sclerotherapy.The total effective rate of 3 months and 6 months after operation was compared between the two groups;Perioperative adverse reactions were observed in two groups;Compare the changes of serum indexes[carbohydrate antigen 125(CA125),carbohydrate antigen 199(CA199)],sex hormones[follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2)]before and 3 months after surgery in the two groups.Results:There was no significant difference in the total effective rate between the two groups 3 months and 6 months after operation(P>0.05);The incidence of abdominal pain,fever and drunkenness like adverse reactions in the observation group was significantly lower than that in the control group(P<0.05);Three months after operation,the serum CA125 level in both groups was lower than that before operation(P<0.05),and that in the observation group was lower than that in the control group(P<0.05);There was no significant difference in serum CA199,FSH,LH,E2before and after operation between the two groups(P>0.05).Conclusion:Ultrasound guided catheter drainage combined with sclerotherapy with poly(cinnamyl alcohol)or absolute ethanol treatment of OEC can achieve satisfactory results,but the adverse reaction of peri o

关 键 词：超声引导 置管引流 聚桂醇硬化 无水乙醇硬化 卵巢子宫内膜异位囊肿 

分 类 号：R445.1[医药卫生—影像医学与核医学] R711.74[医药卫生—诊断学]