青少年L_(3)~S_(2)椎管内恶性蝾螈瘤侵犯骶椎并术后复发1例  

Adolescent L_(3)~S_(2)Intradural Malignant Triton Tumor Invading the Sacral Spine and Recurring after Surgery:Case Report

作　　者：黄文鹏 肖晓燕 李莉明[1] 高剑波[1] HUANG Wen-peng;Xiao Xiao-yan;LI Li-ming;Gao Jian-bo(Department of Radiology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)

机构地区：[1]河南省郑州大学第一附属医院放射科,河南郑州450052

出　　处：《罕少疾病杂志》2023年第2期10-11,共2页Journal of Rare and Uncommon Diseases

基　　金：国家自然科学基金(81971615)。

摘　　要：目的探讨恶性蝾螈瘤的诊断和临床特点,以提高对该病的认识。方法回顾性分析1例经病理证实的L_(3)~S_(2)椎管内恶性蝾螈瘤青少年患者的临床资料,并结合相关文献进行分析。结果患者临床表现为双下肢麻木无力、不能排尿,全麻下行后正中入路L_(3)~S_(2)椎管内占位切除术后病理证实为恶性蝾螈瘤,术后3个月复查MRI发现肿瘤复发,再次行手术切除后行抗肿瘤放射治疗,辅助替莫唑胺胶囊化疗药物,目前仍在随访中。结论恶性蝾螈瘤以根治性手术切除后辅以高剂量放射治疗为主,术后应密切随诊。Objective To investigate the diagnosis and clinical characteristics of malignant triton tumor in order to improve the understanding of the disease.Methods The clinical data of a juvenile patient with malignant triton tumor in L_(3)~S_(2)spinal canal confirmed by pathology were analyzed retrospectively with pertinent literature.Results The clinical manifestations of the patient were numbness and weakness of both lower limbs and inability to urinate.The tumor was confirmed as malignant triton tumor by pathology after L_(3)~S_(2)intraspinal space occupying resection through the posterior median approach under general anesthesia.MRI reexamination 3 months after operation found that the tumor recurred.After surgical resection again,anti-tumor radiotherapy was performed,supplemented with temozolomide capsule chemotherapy.At present,it is still in follow-up.Conclusion Malignant triton tumor is mainly treated by radical resection combined with high-dose radiotherapy,and should be closely followed up after operation.

关 键 词：恶性蝾螈瘤 术后复发 磁共振成像 诊断显像 

分 类 号：R445.2[医药卫生—影像医学与核医学]