苯磺酸左旋氨氯地平联合贝那普利治疗老年急性脑梗死高血压的临床合理用药分析  

Rational Use of Levamlodipine Besylate Combined with Benazepril in the Treatment of Senile Acute Cerebral Infarction Hypertension

作　　者：高长梅[1] 王娟 张新晖 GAO Chang-mei;WANG Juan;ZHANG Xin-hui(Department of Pharmacy,Tianjin Occupational Disease Prevention and Control Hospital,Tianjin 300011,China)

机构地区：[1]天津市职业病防治院药剂科,天津300011

出　　处：《罕少疾病杂志》2023年第2期15-16,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的分析苯磺酸左旋氨氯地平联合贝那普利治疗老年急性脑梗死高血压的临床疗效。方法抽取自2019年1月至2020年12月在我院接受诊断治疗的80例急性脑梗死高血压老年患者为观察对象,按照随机数字表法分为观察组(苯磺酸左旋氨氯地平联合贝那普利,40例)和对照组(盐酸贝那普利片,40例),比较分析两组患者治疗前后血压水平、NIHSS评分,治疗前后血脂水平变化。结果观察组的疗效更加,对照组相对更低于观察组(P<0.05);治疗前,两组患者之间舒张压、收缩压及NIHSS评分对比无明显差异(P>0.05),治疗后,观察组患者舒张压、收缩压及NIHSS评分明显更低(P<0.05);治疗前,两组患者TC、TG、LDL-C水平对比无明显差异(P>0.05),治疗后,观察组患者TC、TG、LDL-C水平明显更低于对照组患者(P<0.05)。结论在老年急性脑梗死高血压患者的临床治疗中,苯磺酸左旋氨氯地平联合贝那普利可发挥出巨大治疗作用,用药后可快速降低并稳定血压,缓解神经功能受损症状,促进患者身体康复,值得临床广泛应用。Objective To analyze the clinical effect of levamlodipine combined with benazepril in treating elderly patients with acute cerebral infarction and hypertension.Methods 80 elderly patients of acute cerebral infarction and hypertension from January 2019 to December 2020 were divided into the observation group(levoamlodipine phenylic acid combined with benenapril,40 cases)and control group(benazapril hydrochloride tablets,40 cases)between the two groups:blood pressure level and NIHSS score,and the change of blood lipid level before and after treatment.Results The observation group was more effective,the control group was relatively lower than the observation group(P<0.05);diastolic,systolic,and NIHSS scores were not different before treatment(P>0.05),diastolic,systolic,and NIHSS scores were significantly lower(P<0.05);before treatment,TC,TG,and LDL-C levels in both groups were not different(P>0.05).After treatment,the TC,TG,and LDL-C levels were significantly lower than those in the control group(P<0.05).Conclusion In the clinical treatment of elderly patients with acute cerebral infarction and hypertension,levoamlodipine combined with benazapril can play a great therapeutic effect,which can quickly reduce and stabilize blood pressure,relieve the symptoms of impaired neurological function,and promote the physical recovery of patients,which is worth widely used in clinical practice.

关 键 词：苯磺酸左旋氨氯地平 贝那普利 老年急性梗死 高血压 

分 类 号：R544.1[医药卫生—心血管疾病]