全瘤体积直方图分析磁敏感信号强度对腮腺良恶性肿瘤的鉴别诊断价值  

The Value of Total Tumor Volume Histogram Analysis of Magnetic Sensitivity Signal Intensity in the Differential Diagnosis of Parotid Benign and Malignant Tumors

作　　者：陆一昕 罗宁斌[1,3,4] 刘丽娟 黄彩云[1,3,4] 李伟 林玲 周传集[1,3,4] 赖少侣 LU Yi-xin;LUO Ning-bin;LIU Li-juan;HUANG Cai-yun;LI Wei;LIN Ling;ZHOU Chuangji;LAI Shao-lv(Department of Radiology,Guangxi Medical University Cancer Hospital,No.71 Hedi Avenue,Nanning 530021,Guangxi,China;Department of Head and neck surgery,Guangxi Medical University Cancer Hospital,Guangxi,China;Guangxi Key Clinical Specialty(Medical imaging Department),Guangxi,China;Dominant Cultivation Discipline of Guangxi Medical University Cancer Hospital(Medical imaging Department),Guangxi,China)

机构地区：[1]广西医科大学附属肿瘤医院医学影像中心,广西南宁530021 [2]广西医科大学附属肿瘤医院头颈外科,广西南宁530021 [3]广西临床重点专科,广西南宁530021 [4]广西医科大学附属肿瘤医院优势培育学科,广西南宁530021

出　　处：《中国CT和MRI杂志》2023年第2期31-34,共4页Chinese Journal of CT and MRI

基　　金：广西影像医学临床医学研究中心建设(桂科AD20238096);多模态磁共振在腮腺肿瘤中的应用价值(2017GXNSFAA198090);颈部肿瘤患者CT增强扫描参数优化选择和对比剂应用安全性研究(Z20190799)。

摘　　要：目的 探讨直方图分析磁敏感信号强度鉴别腮腺良恶性肿瘤的的临床价值。方法 前瞻性的收集分析经过手术病理证实的41例腮腺肿瘤病例,患者均行头颈部SWI、常规MRI扫描,测量直方图磁敏感信号强度相关参数(平均数、中位数、偏斜度、峰度、最小值、最大值、第10、20、30、40、50、60、70、80、90百分位数)。良恶性肿瘤间磁敏感信号强度差异采用独立样本t检验或Mann-Whitney U检验比较。多形性腺瘤、腺淋巴瘤、恶性肿瘤之间磁敏感信号强度比较采用One-Way-ANOVA分析,组内比较使用Tukey检验,不符合正态分布的参数采用Kruskal-Wallis检验,组内比较采用Steel-Dwass检验。腮腺肿瘤形态学特征采用卡方检验进行分析;采用ROC评估全瘤磁敏感信号强度参数及形态学征象鉴别腮腺良恶性肿瘤的能力。结果 腮腺良恶性肿瘤之间比较显示平均数、中位数、偏斜度、最小值、第10、20、30、40、50、60、70、80百分位数及肿瘤边缘、是否侵犯周围结构均有统计学差异(P<0.05)。One-Way-ANOVA显示平均数、中位数、最小值、第10、20、30、40、50百分位数差异有统计学意义(P<0.05)。结论 直方图磁敏感信号强度及形态学征象有助于鉴别腮腺良恶性肿瘤。Objective To explore the clinical value of histogram analysis of magnetic sensitivity signal intensity in distinguishing benign and malignant parotid tumors. Methods Prospective collection and analysis of 41 cases of parotid gland tumors confirmed by surgery and pathology. All patients underwent head and neck SWI and conventional MRI scans,and measured histogram magnetic sensitivity signal intensity related parameters(Mean,median,skewness,kurtosis,minimum,maximum,10th,20th,30th,40th,50th,60th,70th,80th,90th percentile). The difference of magnetic sensitivity signal intensity between benign and malignant tumors was compared by independent sample t test or Mann-Whitney U test. The comparison of magnetic sensitivity signal intensity among pleomorphic adenoma,Warthin tumor and malignant tumor was analyzed by One-Way-ANOVA,Tukey test was used for intra-group comparison,Kruskal-Wallis test was used for parameters that did not conform to the normal distribution,and intra-group comparison was used Steel-Dwass inspection. The morphological characteristics of parotid gland tumors were analyzed by chi-square test;ROC was used to evaluate the ability of the whole tumor’s magnetic sensitivity signal intensity parameters and morphological signs to distinguish benign and malignant parotid gland tumors. Results Comparison between benign and malignant tumors of the parotid gland shows the mean,median,skewness,minimum,10th,20th,30th,40th,50th,60th,70th,80th percentile,tumor edge,and whether it invades surrounding structures There were statistical differences(P<0.05). One-Way-ANOVA analysis showed that the mean,median,minimum,10th,20th,30th,40th,and 50th percentile differences were statistically significant(P<0.05).Conclusion The intensity of the histogram magnetic sensitivity signal is helpful to distinguish benign and malignant tumors of the parotid gland.

关 键 词：直方图 腮腺肿瘤 磁共振成像 磁敏感加权成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]