婴儿型纤维肉瘤的MR表现和Ki67表达分析  

Comparisons of MR Features and Ki67 expressions in Patients with Infantile Fibrosarcomas

作　　者：刘长林 丁宇 李晓燕 曾凡勇 储彩婷[2] 李文华 LIU Chang-lin;DING Yu;LI Xiao-yan;ZENG Fan-Yong;CHU Cai-ting;LI Wen-hua(Department of Medical Imaging,Xinhua Hospital Chongming Branch,Shanghai 202150,China;Department of Radiology,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)

机构地区：[1]新华医院崇明分院医学影像科,上海202150 [2]上海交通大学医学院附属新华医院放射科,上海202150

出　　处：《中国CT和MRI杂志》2023年第2期169-170,177,共3页Chinese Journal of CT and MRI

摘　　要：目的 探讨婴儿型纤维肉瘤(IFs)的MR表现特点和Ki67的表达状态。方法 对11例经手术病理证实的IFs的MR资料进行回顾性分析,对其发生的部位、大小、边界、形态、信号特点、表观弥散系数(ADC)值和强化特征及Ki67表达程度进行研究分析。结果 11例患者中,头颈部3例,肢体7例(上肢前臂3例,上臂1例;下肢腘窝区1例,小腿1例),腹膜后起源1例。肿瘤大小从0.7×1.1×1.2cm到3.0×7.0×9.0cm。11例肿瘤边界规则,呈实性者7例,囊实性者4例。肿瘤实性部分T1WI呈等或稍低信号,T_(2)WI和弥散加权成像(DWI)呈高信号,肿瘤实性部分ADC值范围为0.75~1.12mm^(2)/s。增强后肿瘤实性部分和囊壁呈明显强化。Ki67的表达程度为15%~30%(21.73±6.08%)。结论 婴儿型纤维肉瘤为好发于肢体和头颈部的边界清楚的实性或囊实性肿块,增强后实性部分显著强化,肿瘤Ki67呈低-中表达是其特征。Objective To explore MRI appearances and the expression of Ki67 of infantile fibrosarcomas(IFs). Methods The MR data and the expression of Ki67 of 11patients of histopathologically proven IFs were retrospectively reviewed. The sites,size,border,morphology,imaging features,and apparant diffusion coefficient(ADC) value of lesions were measured and analyzed. Results Of 11 IFs,the masses arisen on head and neck in 3 cases. the limbs in 7( including 3 cases in the forearm of upper limbs,1 case in the upper arm),1 in the popliteal fossa of lower extremity,1 in the calf and 1 in the retroperitoneal region. The ranges in size for the lesions were from 0.7×1.1×1.2cm~3.0×7.0×9.0cm. 11 tumors were all welldefined and 7 was solid and 4 was solid-cystic. The solid components of all tumors were isointensity or slight hypointensity compared to muscle on T1-weighted images and hyperintensity on T2-weighted images and DW imaging with a range of mean ADC value from 0.75~1.12mm^(2)/s. The solid component and cystic wall of the tumors were strong enhancement after administration of contrast medium. The range of expression of Ki67 was 15%~30%(21.73±6.08%). Conclusion IFs were predominantly occurred in limbs and head and neck. The tumor maybe solid or solid-cystic with well-defined margins. The characteristics of MR imaging of IF were isointensity or slight hypointensity to muscle on T1-weighted images and hyperintensity on T2-weighted images with strong enhancement of solid components and low to intermediate expression of Ki67.

关 键 词：婴儿 婴儿型纤维肉瘤 磁共振成像 表观弥散系数 KI67 

分 类 号：R445.2[医药卫生—影像医学与核医学]