基于微纳米金属有机框架的汗液生物传感研究  

Sweat Biosensor Based on the Micro-nano Metal-organic Frameworks

作　　者：陈至威 陈艳霞 秦雷[1] CHEN Zhiwei;CHEN Yanxia;QIN Lei(Beijing Key Laboratory for Sensor,Beijing Information Science&Technology University,Beijing 100101,China)

机构地区：[1]北京信息科技大学传感器北京市重点实验室,北京100101

出　　处：《传感器世界》2022年第12期1-5,I0002,共6页Sensor World

基　　金：北京市自然科学基金项目(No.2214057);国家自然科学基金项目(No.22004009,U2006218);北京市教育委员会科技计划一般项目(No.KM202111232005);促进高校分类发展项目(No.2021YJPY240,2021KYPT117)。

摘　　要：近年来,随着我国经济社会发展水平的不断提高,群众多样化医疗健康需求持续快速增长。汗液检测作为一种无创性分析手段,不仅减小了患者的痛苦,而且降低了感染风险。该研究设计了一种基于微纳米金属有机框架的汗液生物传感界面,介绍了金属有机框架的制备工艺,通过简单的比色法实现了人体汗液中葡萄糖、p H的多组分同时检测。这种基于微纳米金属有机框架的汗液生物传感界面制备简单,成本低廉,稳定性好,灵敏度高。基于微纳米金属有机框架的汗液生物传感界面将为生物传感平台的构建提供新思路,在多组分检测及临床检测领域具有巨大的潜在应用前景。With the socio-economic development, the diverse healthcare needs of people grow rapidly.Sweat detection is a non-invasive analysis, which not only relieves the pain of patients, but also decreases the infection risk. In this study, we designed a sweat biosensing interface based on the micro-nano metalorganic frameworks. The work introduced the preparation process of the metal-organic framework, and realized the simultaneous multicomponent detection of glucose and pH in human sweat by the simple colorimetric method.This sweat biosensing interface greatly enhanced the convenience and reduced the cost, which is sensitive in sweat sensing. The sweat biosensor based on micro-nano metal-organic frameworks will offer a promising means for the design of biosensing platform and have great potential applications in multicomponent biosensing and clinical detection.

关 键 词：金属有机框架 微纳米材料 汗液检测 生物传感 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置]