药源性胸腔积液的研究进展  

Research Progress in Drug-induced Pleural Effusion

作　　者：黄静[1] 丁群力[2] 吴伦[1] HUANG Jing;DING Qunli;WU Lun(The Affiliated Hospital of Medical School of Ningbo University,Department of Pharmacy,Ningbo 315020,China;The Affiliated Hospital of Medical School of Ningbo University,Department of Pulmonary and Critical Care Medicine,Ningbo 315020,China)

机构地区：[1]宁波大学医学院附属医院药学部,浙江宁波315020 [2]宁波大学医学院附属医院呼吸与危重症科,浙江宁波315020

出　　处：《中国现代应用药学》2023年第2期282-288,共7页Chinese Journal of Modern Applied Pharmacy

基　　金：宁波市自然科学基金项目(2018A610278);浙江省病理生理学技术研究重点实验室开放基金(201905)。

摘　　要：药源性胸腔积液是一种少见的药物引起的肺部不良反应。已发现有较多药物会导致胸腔积液的发生,然而目前对药源性胸腔积液的认知尚少,在临床中常常被忽略。本文根据药物引起胸腔积液的相关病例报道和临床研究等文献资料,阐述药源性胸腔积液的发病率、发病机制、临床表现、诊断流程、治疗手段、相关药物等,以期为临床鉴别药源性胸腔积液提供参考。Drug-induced pleural effusion is a rare drug-induced pulmonary adverse reaction.Several drugs have been found to cause pleural effusion,yet drug-induced pleural effusion is still under recognized and often overlooked in clinical practice.This review described the incidence,pathogenesis,clinical manifestations,diagnostic process,treatments and common drugs of drug-induced pleural effusion based on relevant case reports and clinical studies,to provide a clinical reference for the identification of drug-induced pleural effusion.

关 键 词：药源性胸腔积液 嗜酸性胸腔积液 药物狼疮性胸腔积液 肺部不良反应 

分 类 号：R969.3[医药卫生—药理学]