生物医用有色金属材料研究现状与未来发展  

Research Progress and Future Development of Nonferrous Biomedical Materials

作　　者：关绍康[1] 朱世杰[1] 郑玉峰[2] 王云兵 张兴栋 Guan Shaokang;Zhu Shijie;Zheng Yufeng;Wang Yunbing;Zhang Xingdong(School of Materials Science and Engineering,Zhengzhou University,Zhengzhou 450001,China;School of Materials Science and Engineering,Peking University,Beijing 100871,China;National Engineering Research Center for Biomaterials,Chengdu 610064,China)

机构地区：[1]郑州大学材料科学与工程学院,郑州450001 [2]北京大学材料科学与工程学院,北京100871 [3]国家生物医学材料工程技术研究中心,成都610064

出　　处：《中国工程科学》2023年第1期104-112,共9页Strategic Study of CAE

基　　金：国家重点研发计划项目(2021YFC2400700,2016YFC1102400);中国工程院咨询项目“我国先进有色金属材料发展战略研究”(2022-XZ-20);国家自然科学基金联合重点项目(U1804251)。

摘　　要：生物医用有色金属材料发展迅速,形成了适应不同体内环境、不同组织的医用有色金属材料及器件体系;着眼未来开展领域研究规划,提升新型医用有色金属材料及器件的临床应用水平,兼具理论研究与实践应用价值。本文论述了生物医用有色金属材料在耐蚀性、耐磨性、疲劳强度及韧性、生物适配性等方面的关键性能要求,系统梳理了永久性植入有色金属材料、生物可降解有色金属材料、多孔医用有色金属材料、医用有色金属表面改性等细分领域的研究进展、发展趋势与科学问题。在凝练各类生物医用有色金属材料未来研究方向的基础上,提出了加强基础与关键核心技术研究、组建“产学研医监”协同创新体、建立相关标准及规范、培育高精尖人才体系等发展建议,以期为新型材料发展布局与前沿技术研发提供先导性参考。Nonferrous biomedical materials have developed rapidly in recent years.A variety of new nonferrous biomedical materials and devices that adapt to different in vivo environments and tissues have been developed.It is of both theoretical and practical values to make research plans to improve the clinical application level of new nonferrous biomedical materials and devices.This study clarifies the key performance requirements of the nonferrous biomedical materials,regarding corrosion resistance,wear resistance,fatigue strength and toughness,and biocompatibility.The research progress,development trend,and scientific issues of nonferrous medical materials for permanent implants,biodegradable nonferrous medical materials,porous nonferrous medical materials,and surface modification of nonferrous medical materials are reviewed.After summarizing the future research directions of various nonferrous biomedical materials,this study proposes the following development suggestions:(1)strengthening basic research and the development of key core technologies,(2)establishing a collaborative innovation community that integrates industry,education,research,medicine,and supervision,(3)formulating relevant standards and evaluation norms,and(4)developing a highly skilled professional training system,thereby providing a guiding reference for developing the new material industry and relevant cutting-edge technologies.

关 键 词：生物医用有色金属材料 永久性植入有色金属材料 生物可降解有色金属材料 多孔医用有色金属材料 医用有色金属表面改性 

分 类 号：TG146[一般工业技术—材料科学与工程]