四神丸合补中益气汤治疗慢性腹泻的临床疗效观察  

Clinical observation of Sishen Pill combined with Buzhong Yiqi Decoction in treating chronic diarrhea

作　　者：朱媛媛[1] 樊威伟[2] 何亚鑫 ZHU Yuanyuan;FAN Weiwei;HE Yaxin(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital,Tianjin 300120,China)

机构地区：[1]天津中医药大学,天津301617 [2]天津市中医药研究院附属医院,天津300120

出　　处：《天津中医药》2023年第2期155-158,共4页Tianjin Journal of Traditional Chinese Medicine

基　　金：天津市卫生健康委员会中医药重点领域科研项目(2020002)。

摘　　要：[目的]观察研究对比治疗脾肾阳虚型慢性腹泻时应用四神丸合补中益气汤的临床疗效,探讨四神丸合补中益气汤治疗脾肾阳虚型慢性腹泻的优势所在。[方法]收集2019—2022年天津市中医药研究院附属医院肾病门诊60例符合脾肾阳虚型慢性腹泻的患者,采用随机对照试验方法,随机分为治疗组和对照组,每组30例。治疗组予以四神丸合补中益气汤加减进行治疗,对照组则服用双歧杆菌三联活菌肠溶胶囊进行治疗,并对两组患者治疗前后的主症、次症积分的变化以及临床疗效进行观察比较。[结果]治疗后治疗组的大便次数、大便形态、纳呆食少、神疲乏力相较于对照组症状改善更加明显,临床疗效显著。[结论]应用四神丸合补中益气汤治疗方法对脾肾阳虚型慢性腹泻患者的临床症状有良好改善效果,对提高临床实践有积极作用。[Objective]To observe and compare the clinical efficacy of Sishen Pills combined with Buzhong Yiqi Decoction in the treatment of chronic diarrhea with spleen-kidney yang deficiency,to discuss the advantages of Sishen Pills combined with Buzhong Yiqi Decoction in the treatment of chronic diarrhea with spleen-kidney yang deficiency.[Methods]The 60 patients with chronic diarrhea of spleen-kidney yang deficiency from nephropathy outpatient department of Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital from 2019 to 2022 were included in the study.The randomized controlled trial method was used and they were randomly divided into a treatment group consisting of 30 patients and a control group consisting of 30 patients.Sishen Pills and Buzhong Yiqi Decoction were used in the treatment group,while the control group was treated with Bifidobacterium triple viable enteric-coated capsules in the same treatment course,and the symptom scores and clinical efficacy changes between the two groups before and after treatment were analyzed and compared.[Results]After treatment,the symptoms of stool number,stool morphology,sluggishness and fatigue in the treatment group were statistically significant(P<0.05),and the efficacy was better.[Conclusion]The treatment method of Sishen Pills combined with Bu zhona Yiai Decoction has a significant improvement effect on the clinical symptoms of patients with spleen and kidney yang deficiency chronic diarrhea,which can enhance the clinical efficacy.

关 键 词：四神丸 补中益气汤 脾肾阳虚 慢性腹泻 

分 类 号：R256.34[医药卫生—中医内科学]