新生儿单纯疱疹病毒Ⅰ型重症肺炎1例并文献复习  

A case of neonatal herpes simplex virus type Ⅰ severe pneumonia and literature review

作　　者：曹芳[1] 叶同生 冯广彬 华山 王昶 CAO Fang;YE Tong-sheng;FENG Guang-bin;HUA Shan;WANG Chang(Department of Respiratory Medicine,Anhui Children's Hospital,Pediatric Hospital Affiliated to Fudan University,Hefei,Anhui 233000,China;不详)

机构地区：[1]复旦大学附属儿科医院安徽医院安徽省儿童医院呼吸科,安徽合肥233000 [2]复旦大学附属儿科医院安徽医院安徽省儿童医院新生儿科 [3]阜阳市颍上县人民医院儿科,安徽阜阳236200 [4]复旦大学附属儿科医院安徽医院安徽省儿童医院影像中心

出　　处：《中华全科医学》2023年第2期354-356,共3页Chinese Journal of General Practice

摘　　要：本文报告单纯疱疹病毒(herpes simplex virus, HSV)Ⅰ型感染新生儿重症肺炎1例并文献复习。该新生儿以“气促、口吐泡沫、呛奶”呼吸系统表现为主,肺部CT提示双肺呈广泛弥漫性网格影改变,临床较少见,经及时诊断及给予更昔洛韦静滴联合干扰素雾化抗病毒及支持治疗,患儿恢复良好,出院随访1年,生长发育正常。A case of severe neonatal pneumonia infected by herpes simplex virus(HSV) type Ⅰ was reported and the literature was reviewed. The respiratory system of the neonate was mainly manifested as "shortness of breath, foaming at the mouth, and choking milk". The Lung CT indicated that both lungs presented widespread diffuse grid changes, which was rare in clinic. After timely diagnosis and ganciclovir intravenous drops combined with interferon atomization antiviral and supportive treatment, the child recovered well, and was discharged with normal growth and development at 1 year follow-up.

关 键 词：新生儿 单纯疱疹病毒 重症肺炎 宏基因 Α干扰素 

分 类 号：R722.1[医药卫生—儿科]