体检人群甲状腺结节彩色多普勒超声特征的横断面调查  

Cross-sectional investigation of thyroid nodule characteristics under color Doppler ultrasound in the physical examination population

作　　者：乔雪 李静蔚[2] 蔡碧娥 刘杨[2] 陈翰翰[2] 陈宏志[4] Qiao Xue;Li Jingwei;Cai Bi'e;Liu Yang;Chen Hanhan;Chen Hongzhi(The First Clinical Medical College,Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Department of Breast and Thyroid Surgery,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Health Management Department of Preventive Treatment Center,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China;School of Rehabilitation Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

机构地区：[1]山东中医药大学第一临床医学院,济南250014 [2]山东中医药大学附属医院乳腺甲状腺外科,济南250014 [3]山东中医药大学附属医院治未病中心健康管理部,济南250014 [4]山东中医药大学康复医学院,济南250355

出　　处：《中国医药》2023年第1期47-51,共5页China Medicine

基　　金：山东省医药卫生科技发展计划项目(202016001022)。

摘　　要：目的分析体检人群甲状腺结节彩色多普勒超声的疾病特征。方法收集2018年8月至2021年10月在山东中医药大学附属医院治未病中心参加体检并行甲状腺彩色多普勒超声检查的17384名体检者的相关资料,分析甲状腺结节在不同年龄及性别人群中的检出情况,并对结节数量、位置、最大直径、甲状腺影像报告和数据系统(TI-RADS)分类等结节特征进行比较。结果17384名体检者中,检出甲状腺结节者8192名,检出率47.12%;男性检出率42.45%(3866/9107),女性检出率为52.27%(4326/8277);女性甲状腺结节检出率整体高于男性,差异有统计学意义(P<0.001)。甲状腺结节检出率随着年龄的增长而增高(趋势χ^(2)=1572.454,P<0.001);各年龄段甲状腺结节检出率相比,差异有统计学意义(P<0.001)。8192名检出甲状腺结节者中,单发结节3261名(39.81%),多发结节4931名(60.19%);单侧结节4702名(57.40%),双侧结节3490名(42.60%);<10 mm结节6562名(80.10%),10~<20 mm结节1269名(15.49%),≥20 mm结节361名(4.41%);TI-RADS 2类结节2092名(25.54%),TI-RADS 3类结节5577名(68.08%),TI-RADS 4类结节523名(6.38%)。结节数量、位置、最大直径及TI-RADS分类在不同性别间差异均有统计学意义(均P<0.05)。结论体检人群甲状腺结节检出率较高,并随年龄增长而逐渐升高,女性显著高于男性,以多发、单侧、直径<10 mm、TI-RADS 3类结节为主。Objective To analyze the thyroid nodule characteristics under color Doppler ultrasound in the physical examination population.Methods From August 2018 to October 2021,relevant information of 17384 examinees who had thyroid color Doppler ultrasound exam in Preventive Treatment Center,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine were collected.The detection of thyroid nodules in different ages and genders was analysis,and the nodule characteristics such as the number,location,size,and thyroid imaging reporting and data system(TI-RADS)classification were compared.Results Among 17384 examinees,8192 cases had thyroid nodules,and the detection rate was 47.12%.The detection rate was 42.45%(3866/9107)for men,and 52.27%(4326/8277)for women;the overall detection rate of thyroid nodules in women was higher than that in men(P<0.001).The detection rate of thyroid nodules increased with ageing(trend χ^(2)=1572.454,P<0.001);the detection rate of thyroid nodules was statistically significant among different ages(P<0.001).There were 3261 cases(39.81%)of single nodule and 4931 cases(60.19%)of multiple nodules among 8192 examinees with thyroid nodules.Unilateral nodules were 4702 cases(57.40%),and bilateral nodules were 3490 cases(42.60%).There were 6562 cases(80.10%)with nodule diameter<10 mm,1269 cases(15.49%)with 10-<20 mm,and 361 cases(4.41%)with≥20 mm.TI-RADS class 2 was 2092 cases(25.54%),TI-RADS class 3 was 5577 cases(68.08%),and TI-RADS class 4 was 523 cases(6.38%).There were statistical differences in the number,location,maximum diameter,and TI-RADS classification of nodules between genders(all P<0.05).Conclusions The detection rate of thyroid nodules is high in examinees,and gradually increases with ageing.The detection rate in women is significantly higher than that in men.Thyroid nodules are mainly multiple,unilateral,diameter<10 mm,and TI-RADS class 3.

关 键 词：甲状腺结节 健康体检 流行病学 横断面研究 

分 类 号：R181.3[医药卫生—流行病学]