静脉-静脉体外膜肺氧合联合血液净化成功救治重度乙二醇中毒1例  

A case of severe ethylene glycol poisoning treated successfully by V-V ECMO combined with blood purification

作　　者：潘勇莉 吕世进[1] 蒋镇宏 Pan Yongli;Lyu Shijin;Jiang Zhenhong(Department of Emergency,the Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China)

机构地区：[1]杭州师范大学附属医院急诊科,杭州310015

出　　处：《中华劳动卫生职业病杂志》2022年第12期947-949,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：乙二醇别名甘醇,是汽车使用的常用低温防冻液,常温环境下为一种无色、无臭、挥发性低有甜味的黏稠液体,容易经过消化道被分解并吸收,产生毒性代谢产物引起严重的中枢神经系统抑制、代谢性酸中毒、心肺症状以及肾功能不全等临床症状,甚至死亡。误服和口服自杀是当前乙二醇中毒的主要病因。本文报道2021年12月杭州师范大学附属医院急诊科收治的重度乙二醇中毒病例1例。经静脉-静脉体外膜肺氧合(V-V ECMO)联合血液净化等治疗后好转出院。Ethylene glycol,also known as glycol,is a common low-temperature antifreeze used in automobiles.It is a colorless,odorless,volatile,low-sweet,sticky liquid at room temperature.Ethylene glycol is easily decomposed and absorbed through the digestive tract.Toxic metabolites cause serious clinical symptoms such as central nervous system inhibition,metabolic acidosis,cardiopulmonary symptoms and renal insufficiency,and even death.Misuse and oral suicide are the main causes of ethylene glycol poisoning.This article reports a case of severe ethylene glycol poisoning admitted to the emergency department of the Affiliated Hospital of Hangzhou Normal University in December 2021.After treatment with V-V ECMO combined with blood purification,the patient was improved and discharged from hospital.

关 键 词：中毒 乙二醇 血液净化 静脉-静脉体外膜肺氧合 中枢神经系统抑制 急性呼吸窘迫综合征 肾功能不全 

分 类 号：R595.6[医药卫生—内科学]