新疆维吾尔自治区农村地区人群身体肥胖指标与心脏代谢危险因素的关联性研究  

The association between adiposity indicators and cardiometabolic risk factors among adults in rural areas of Xinjiang Uygur Autonomous Region

作　　者：吴涛 马儒林[1,2] 胡云华 郭恒[1,2] 张向辉 何佳[1,2] 闫贻忠 芮东升[1,2] 木拉提 牛强[1,2] 王馨平 马娇龙 丁玉松[1,2] 刘佳铭[1,2] 张眉[1,2] 李毓 王海霞 郭淑霞 WU Tao;MA Ru-lin;HU Yun-hua;GUO Heng;ZHANG Xiang-hui;HE Jia;YAN Yi-zhong;RUI Dong-sheng;MU La-ti;NIU Qiang;WANG Xin-ping;MA Jiao-long;DING Yu-song;LIU Jia-Ming;ZHANG Mei;LI Yu;WANG Hai-xia;GUO Shu-xia(Department of Public Health,School of Medicine,Shihezi University,Shihezi,Xinjiang Uygur Autonomous Region 832000,China)

机构地区：[1]石河子大学医学院预防医学系,新疆维吾尔自治区石河子832000 [2]石河子大学医学院第一附属医院中亚高发病防治重点实验室

出　　处：《中国预防医学杂志》2022年第12期888-896,共9页Chinese Preventive Medicine

基　　金：国家自然科学基金(81560551);兵团重点领域科技攻关计划(2021AB030)。

摘　　要：目的 探索新疆维吾尔自治区农村地区成年人身体肥胖指标与心脏代谢危险因素的关联。方法 本研究在2010和2016年采用四阶段分层整群随机抽样方法,在新疆维吾尔自治区喀什、伊犁、克孜勒苏柯尔克孜、新疆生产建设兵团第三师和第八师进行现场调查。调查内容包括:问卷调查、体格检查和血样本采集。根据纳入标准最终选择研究对象20 684人。采用logistic回归探讨体质量指数(body mass index, BMI)、身体形态指数(a body shape index, ABSI)、身体圆度指数(body roundness index, BRI)、腹部容积指数(abdominal volume index, AVI)、锥度指数(conicity index, CI)、身体肥胖指数(body adiposity index, BAI)、身体肥胖估计量(body adiposity estimator, BAE)和体脂百分比(body fat percentage, BF%)与糖尿病、高血压、高总胆固醇血症、高三酰甘油血症、高低密度脂蛋白血症、低高密度脂蛋白血症和危险因素聚集的关联性;采用ROC曲线下面积评价指标对心脏代谢危险因素的预测价值。结果 在纳入研究的8个指标中,BAE对糖尿病、高血压、高总胆固醇血症、高三酰甘油血症、高低密度脂蛋白血症、低高密度脂蛋白血症和危险因素聚集的关联最高,每增加一个标准差的OR(95%CI)值分别为2.14(1.95~2.35)、1.97(1.88~2.08)、1.70(1.60~1.81)、2.46(2.32~2.62)、1.78(1.64~1.94)、1.35(1.28~1.42)、2.24(2.12~2.37),其他关联度较高的指标依次为BF%、AVI、BRI和BMI,ABSI与心脏代谢危险因素和危险因素聚集有着最弱的关联。结论 在新疆维吾尔自治区农村地区人群中,BAE可作为简便的指标对心脏代谢危险因素进行预防,从而尽早发现高危个体。Objective To explore the association between adiposity indicators and cardiometabolic risk factors among adults in rural areas of Xinjiang Uygur Autonomous Region.Methods In 2010 and 2016,the fourstage stratified cluster sampling method was used to recruit study participants in Kashgar,Yili,Kizilsu Kirgiz,and the 3rd and 8th Divisions of the Corps.The field surveys were conducted including questionnaire survey:physical examination and blood sample collection.A total of 20 684 participants who met the inclusion criteria were recruited.Logistic regression was used to explore the association of body mass index(BMI),body shape index(ABSI),body roundness index(BRI),abdominal volume index(AVI),conicity index(CI),body adiposity index(BAI),body adiposity estimator(BAE) and body fat percentage(BF%) with diabetes,hypertension,hypercholesterolemia,hypertriglyceridemia,high low density lipoproteinemia,low high density lipoproteinemia and risk factor aggregation,the area under the ROC curve(AUC) was used to evaluate the predictive value of the indicators for cardiometabolic risk factors.Results Among the above 8 body adiposity indices,BAE was highly associated with diabetes,hypertension,hypercholesterolemia,hypertriglyceridemia;high low density lipoproteinemia,low high density lipoproteinemia and risk factor aggregation,with single standard deviation increase,the OR(95 % CI) values were 2.14(1.95-2.35),1.97(1.88-2.08),1.70(1.60-1.81),2.46(2.32-2.62),1.78(1.64-1.94),1.35(1.28-1.42),2.24(2.12-2.37),respectively.While ABSI had the weakest association with cardiometabolic risk factors and risk factor aggregation.Conclusions Among adults in rural areas of Xinjiang Uygur Autonomous Region,BAE can be used as a simple indicator to predict cardiometabolic risk factors and to identify high-risk individuals as early as possible.

关 键 词：身体肥胖指标 心脏代谢危险因素 农村地区 体质量指数 

分 类 号：R181.2[医药卫生—流行病学]