参芪辛夷颗粒治疗儿童脾气虚弱型变应性鼻炎的疗效观察  

Efficacy observation of Shenqi Xinyi granules on allergic rhinitis with spleen-qi weakness type in children

作　　者：李海娇[1] 陈筱琪[1] 陈茜 LI Haijiao;CHEN Xiaoqi;CHEN Qian(Department of Pediatrics,Taizhou Hospital of Traditional Chinese Medicine,Taizhou,Zhejiang 318000,China)

机构地区：[1]台州市中医院儿科,浙江台州318000

出　　处：《现代医药卫生》2023年第4期595-598,共4页Journal of Modern Medicine & Health

基　　金：台州市科学技术局2020年台州市第二批社会发展科技计划项目(20ywb93)。

摘　　要：目的 探讨参芪辛夷颗粒治疗儿童脾气虚弱型变应性鼻炎的临床疗效。方法 选取2017年12月至2020年1月该院收治的脾气虚弱型变应性鼻炎患儿104例,按随机数字表法将其分为对照组和观察组,每组52例。对照组患儿接受氯雷他定糖浆治疗,观察组在对照组基础上给予参芪辛夷颗粒内服。2组连续治疗4周。比较2组临床疗效、临床症状评分、脾气虚弱证症状评分、鼻腔分泌物嗜酸性粒细胞(EOS)计数及血清免疫球蛋白E(IgE)水平。结果 观察组总有效率为92.31%,显著高于对照组的75.00%,差异有统计学意义(P<0.05)。治疗后,2组患儿的临床症状和脾气虚弱证症状评分较治疗前明显降低,且观察组明显低于对照组,差异均有统计学意义(P<0.01)。治疗后,2组患儿的鼻腔分泌物EOS计数和血清IgE水平较治疗前明显降低,且观察组明显低于对照组,差异均有统计学意义(P<0.01)。结论 在西医常规治疗基础上参芪辛夷颗粒治疗儿童脾气虚弱型变应性鼻炎的疗效显著,能明显改善临床症状和中医证候。Objective To investigate efficacy of Senqi Xinyi granules on allergic rhinitis with spleen-qi weakness type in children.Methods A total of 104 children with allergic rhinitis with spleen-qi weakness type treated in this hospital from December 2017 to January 2020 were randomly divided into two groups according to random number table method, with 52 cases in each group.The control group received loratadine syrup, and the observation group was given with Senqi Xinyi granules on the basis of the control group.The two groups were treated continuously for four weeks.Clinical efficacy, clinical symptoms score, symptom score of spleen-qi weakness type, eosinophil(EOS) count of nasal secretions and serum immunoglobulin E(IgE) level were compared between the two groups.Results The total effective rate of the observation group was 92.31%,which was significantly higher than 75.00% of the control group(P<0.05).After treatment, the scores of clinical symptoms and spleen-qi weakness type in the two groups were significantly reduced, and the scores of clinical spleen-qi weakness type in the observation group were significantly lower than those in the control group(P<0.01).After treatment, the nasal secretion EOS count and serum level of IgE in the two groups were significantly decreased, and the nasal secretion EOS count and serum level of IgE in the observation group were significantly lower than the control group, with statistical significance(P<0.01).Conclusion On the basis of conventional western medicine treatment, the treatment of Senqi Xinyi granules has a remarkable effect on the treatment of allergic rhinitis in children with spleen-qi weakness type, and can significantly improve the clinical symptoms and traditional Chinese medicine syndromes.

关 键 词：参芪辛夷汤颗粒 变应性鼻炎 脾气虚弱证 免疫球蛋白E 

分 类 号：R72[医药卫生—儿科]