一种造成男性泌尿生殖道感染的机会致病菌——解葡萄糖苷棒杆菌  

Corynebacterium glucuronolyticum--an opportunistic pathogenic bacterium that causes genitourinary tract infections in males

作　　者：张旺 杨宁 王欢 刘明 张甜 鲍春梅 ZHANG Wang;YANG Ning;WANG Huan;LIU Ming;ZHANG Tian;BAO Chun-mei(Department of Clinical Laboratory,the Fifth Medical Center,Chinese PLA General Hospital,Beijing 100039,China)

机构地区：[1]解放军总医院第五医学中心检验科,北京100039

出　　处：《军事医学》2022年第12期955-960,共6页Military Medical Sciences

基　　金：“科技助力经济2020”重点专项(SQ2020YFF0404184)。

摘　　要：越来越多的证据表明,棒杆菌属的致病力被低估了,该类菌属甚至能使无易感因素的免疫活性个体发生感染。棒杆菌属作为重要的机会致病菌逐渐被人们深入认知,近年来,相继有解葡萄糖苷棒杆菌引起男性泌尿生殖道感染的病例报道。解葡萄糖苷棒杆菌对男性的泌尿生殖道表现出一定的特异性,其作为一种机会致病菌,能引起男性非淋菌性尿道炎、慢性细菌性前列腺炎、无诱发因素的持续性或反复性膀胱炎等泌尿生殖道感染性疾病。该文主要从解葡萄糖苷棒杆菌的生物学特点、流行病学特点、可能的致病机制、临床意义及相关抗菌药物敏感性等方面对相关文献进行综述,以期为患者的诊断和治疗提供科学的理论遵循。There is growing evidence that the pathogenicity of Corynebacterium has been underestimated,and that this group of bacteria can even infect immunocompetent individuals without susceptible factors.Corynebacterium has come to be recognized as important opportunistic pathogenic bacteria.In recent years,there have been successive cases of genitourinary tract infections in males caused by C.glucuronolyticum that not only shows specificity for the genitourinary tract of males,but,as an opportunistic pathogenic bacterium,can cause male non-gonococcal urethritis,chronic bacterial prostatitis,persistent or recurrent cystitis without precipitating factors and other genitourinary tract infectious diseases.This paper reviews literature related to C.glucuronolyticum in terms of biological characteristics,epidemiological characteristics,possible pathogenic mechanisms,clinical significance and related antibacterial drug sensitivity of the bacteriumin order to provide data for the diagnosis and treatment of patients.

关 键 词：解葡萄糖苷棒杆菌 男性 泌尿生殖道感染 非淋菌性尿道炎 前列腺炎 膀胱炎 

分 类 号：R69[医药卫生—泌尿科学]